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NCT ID: NCT05367947 Completed - Multiple Sclerosis Clinical Trials

In-phase Bilateral Exercises in People With Relapsing Remitting Multiple Sclerosis

Start date: March 10, 2023
Phase: N/A
Study type: Interventional

Relapsing-remitting multiple sclerosis (RRMS) is associated with changes of the corticospinal tract integrity, which is quantified by means of corticospinal plasticity. Several factors, such as exercise and interlimb coordination can influence such corticospinal plasticity. Previous work in healthy and in stroke participants showed that the greatest improvement of corticospinal plasticity occurred during in-phase bilateral arm exercises. Here, the investigators propose a concurrent multiple baseline design study which has the advantage to verify the cause-effect inference by the staggered duration through separate baseline phases. The proposed study includes five people with RRMS, who will follow an intervention protocol which includes in-phase bilateral movements of the upper limbs, adapted to different sports activities and to functional training. The aim of the study is to investigate the effects of in-phase bilateral exercises on corticospinal plasticity and on clinical measures, using transcranial magnetic stimulation and standardized clinical assessment. To meet quality standards, the present study has been designed and will be conducted according to the "What Works Clearinghouse" criteria for single case studies.

NCT ID: NCT05328830 Completed - Performance Clinical Trials

Soft Tissue Mobilization Effects on Doms

Start date: January 4, 2022
Phase: N/A
Study type: Interventional

Aim: The aim of the study was to examine and compare the time-dependent effects of IASTM and FR applications on delayed muscle pain and physical performance. Method: 50 physically active healthy male individuals between the ages of 20-35 will be included in the study. Participants will be divided into 3 separate groups as instrument assisted soft tissue mobilization(IASTM), foam roller (FR) and control group. DOMS creation protocol will be implemented after preliminary evaluation. IASTM and FR groups will be treated after the formation of doms. The control group will not be applied. participants are evaluated 1 day before the doms were created and at 24, 48 and 72 hours after doms created. Subjetcs were tested for physical activity level with IPAQ-SF, flexibility with sit and reach test, pain with Visual analog scale, edema with thigh circumference measurement, explosive power with horizontal and vertical jump test, dynamic balance with y balance test and isokinetic muscle strength of the quadriceps and hamstring muscles with isokinetic dynamometer.

NCT ID: NCT05300061 Completed - Specific Phobia Clinical Trials

Values Interventions for Increasing Engagement With What is Feared in Individuals With Specific Phobias

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Exposure is considered the therapy of choice for specific phobias (SPs). Nevertheless, therapy engagement is extremely limited. SPs are maintained through avoidance of feared stimuli and as such willingness to approach what is feared constitutes a key factor that could explain limited treatment engagement. Values interventions, a key element of acceptance and commitment therapy (ACT), might be one way to increase engagement, yet to this date limited research exists in this area. For the purposes of the current study, two brief values interventions were developed: (a) a personal and (b) a prosocial one. These will be compared to (c) a no-instructions control in increasing willingness to approach and approach behaviour towards phobic stimuli. Ninety participants with flying phobia will be randomly allocated to one of the three groups. To measure willingness to engage with feared stimuli and approach behaviour two behavioural approach tasks using novel technologies (virtual reality), which aimed to expose participants to situations analogous to real life, were developed. Willingness and behavioural approach towards airplanes at a one month follow up will also be assessed. Therefore, it is hypothesised that: 1. Participants in either of the two values intervention groups will have greater willingness to engage and approach behaviour towards feared stimuli compared to those in control, during the study tasks. 2. Participants in either of the two values intervention groups will have greater willingness to engage and approach behaviour towards feared stimuli compared to those in control at follow up. Additionally, as prosocial values provide an evolutionary advantage, the second study aim was to identify if they lead to greater engagement with phobic stimuli compared to personal ones. Therefore, it was also hypothesised that: 3. Participants in the prosocial values group will have greater willingness to engage and approach behaviour towards feared stimuli compared to those in personal values group, both during the study tasks and at follow up. 4. Participants in the prosocial values group will have greater willingness to engage and approach behaviour towards feared stimuli compared to those in personal values group at follow up.

NCT ID: NCT05271175 Completed - Smoking Cessation Clinical Trials

Accelerated iTBS in Smoking Cessation

Start date: April 19, 2019
Phase: N/A
Study type: Interventional

Cigarette smoking is one of the foremost causes of preventable disease and premature death. In 2014, 68% of adult smokers wanted to quit smoking and in 2017, 55.1% of adult smokers had made a quit attempt. However, only a small percentage of adult smokers (7,4%) achieved to quit smoking. Transcranial magnetic stimulation (TMS) is a novel, powerful, non-invasive brain stimulation therapy. This study used Theta Burst Stimulation (TBS), a newer form of rTMS protocol that can be delivered in a shorter duration compared to the standard rTMS protocol, while delivering a comparable number of pulses. It is a tolerable, powerful, and useful tool in non-invasive brain stimulation therapies. This double-blind randomized control trial evaluated the efficacy of 4 iTBS sessions per day during 5 consecutive days over the left DLPFC in smoking cessation. Moreover, it investigated whether the exposure to smoking-related cues during the rTMS treatment, compared to neutral cues impact cigarette craving.

NCT ID: NCT05246826 Completed - Chronic Neck Pain Clinical Trials

Comparison of Pilates and Conventional Treatment in Addition to Pilates in Patients With Chronic Neck Pain

Start date: February 9, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of clinical pilates exercises and electrotherapy on pain level, physical condition, functional status and psychosocial status in patients with chronic neck pain.In the study, individuals will be divided into two groups. Pilates will be applied to one group for 6 weeks, pilates and conventional therapy will be applied to one group. Individuals will be evaluated before and after treatment. In the evaluation, pain, disability, anxiety and depression status, quality of life of individuals will be questioned. In addition, cervical joint range of motion and endurance will be evaluated.

NCT ID: NCT05225129 Completed - Clinical trials for Physical Performance

Effects Of Blood Flow Restriction Exercise Applications On Physical Fitness Parameters

Start date: January 17, 2022
Phase: N/A
Study type: Interventional

Aim: The aim of the study; during the non-race season, blood flow-restricted exercises applied in addition to routine training programs to determine the effects on physical fitness parameters and sportive motivation of male canoe athletes aged 18 and over and to compare the results between the groups. Method: Male athletes aged 18 and over who are licensed and actively engaged in canoeing in Turkey will be included in the study. Subjects will be divided into two groups , training and control. The training group will be given blood flow restricted exercise for 8 weeks and resistance training equivalent to 30% of 1 maximum repetition. In the control group, 30% of 1 MT of resistance training will be applied for 8 weeks without blood flow restriction. Before and after, athletes will be evaluated with sport-specific performance tests, muscle thickness measurement with ultrasound, isokinetic measurement of hamstring and quadriceps muscles at a speed of 60°/sec and 300°/sec. In addition, the muscles of the athletes will be evaluated with dynamic muscular measurements.

NCT ID: NCT05187702 Completed - Clinical trials for Hypertension and Balance

The Effect of Functional Exercise Training on Patients With Hypertension

Start date: June 28, 2022
Phase: N/A
Study type: Interventional

It is the ability to keep and maintain the body training balance control center. Dynamic balance is the ability to maintain an individual's static position while the movement and posture are active while static. With aging, it is thought that the system will be applied in practice. Control of cerebral blood flow and synapse, which decreases with advanced age and hypertension, continues. In addition to slowing down in mental functions such as memory and learning, it progresses and accelerates in the sense of vibration, nerve velocity, proprioceptor feedback under skin receptor control, and can occur in static, dynamic and isokinetic muscle strength. This causes you to continue the preparations for the necessary evaluations in your postural stability and you watch. Particularly geriatrics reported that Otogo supports us to improve balance in us. The purpose of this goal is to test in otago educational work on static and dynamic movements, lower hypertensive muscle work, capacity and capacity and competence.

NCT ID: NCT05187468 Completed - Clinical trials for Myofascial Pain Syndrome

The Effectiveness of Radial ESWT on Upper Trapezius Mtrps

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

This study looked after the effectiveness of radial ESWT on upper trapezius mtrps. There were three intervention groups which recieved either ESWT or standard care. VAS, PPT, Neck ROM and Cervical functionality were the main outcomes.

NCT ID: NCT05169138 Completed - Labor Pain Clinical Trials

The Effect Of Lavender Essential Oil On Birth Pain

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The study was planned as a randomized controlled trial to determine the effect of lavender oil applied to primiparous women by inhalation and massage methods on labor pain.

NCT ID: NCT05149885 Completed - Asthma Clinical Trials

A Feasibility Study of SenseGuard to Assess Airway Responsiveness During Methacholine Challenge Test (MCT)

Start date: November 4, 2021
Phase: N/A
Study type: Interventional

SenseGuard (SG) is an innovative device for respiratory monitoring. At this study SG measurement will be integrated in a Methacholine Challenge Test (MCT) for monitoring changes in airway obstruction occurred during MCT in parallel to spirometry.