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NCT ID: NCT05563207 Completed - Clinical trials for Acute Myeloid Leukemia

Application of Health Education Path of Traditional Chinese Medicine Nursin

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

To explore the effect of traditional Chinese medicine (TCM) health education standard path on the treatment of patients with acute myeloid leukemia (AML). A total of 60 patients with acute myeloid leukemia in Shijiazhuang Ping An Hospital were selected and divided into control group (n=30) and observation group (n=30) according to the time of admission. Both groups received the same chemotherapy, the control group received routine nursing, and the observation group received TCM health education standard path intervention. The scores of Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), Spitzer Quality of Life Index (QLI), awareness of TCM health education standard path content and nursing satisfaction were compared between the two groups.

NCT ID: NCT05563012 Recruiting - Clinical trials for Disorder in Complete Remission in Response to Treatment

Short-course Radiotherapy Combined With Neoadjuvant Chemotherapy and PD-1 Inhibitor in the Treatment of Locally Advanced Gastric Adenocarcinoma

Start date: September 26, 2022
Phase: Phase 2
Study type: Interventional

This is a Prospective, Single-center, Single-arm, phase II clinical trial to explore the efficacy and safety of sintilimab (PD1 inhibitor) combined with XELOX chemotherapy, evaluate the pathological complete response rate of short-course radiotherapy combined with sintilimab and XELOX chemotherapy in neoadjuvant therapy for locally advanced gastric adenocarcinoma.

NCT ID: NCT05562947 Recruiting - Clinical trials for Neovascular Age Related Macular Degeneration

A Study Of The Efficacy, Safety, And Pharmacokinetics Of The Port Delivery System With Ranibizumab In Chinese Patients With Neovascular Age-Related Macular Degeneration

Start date: June 28, 2024
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy, safety, and pharmacokinetics of ranibizumab 100 mg/mL delivered Q24W via the PDS implant compared with ranibizumab 0.5 mg delivered as a Q4W intravitreal injection in Chinese patients with nAMD.

NCT ID: NCT05562934 Active, not recruiting - Clinical trials for Resistant Hypertension

An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients.

Start date: November 8, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this 20-week randomized double-blind study in patients with resistant hypertension (rHTN) is to evaluate the efficacy, safety, and tolerability, of different doses of XXB750 administered as subcutaneous (SC) injections, compared to placebo. Since all study participants will be patients with rHTN, all study treatments will be given on top of maximally tolerated background antihypertensive therapy recommended by international guidelines for treatment of HTN (i.e., a thiazide or a thiazide-like diuretic, an angiotensin converting enzyme inhibitor (ACEi) or an angiotensin receptor blocker (ARB), and a long-acting dihydropyridine calcium channel blocker (CCB).

NCT ID: NCT05562622 Active, not recruiting - Myopia Clinical Trials

Assessment of DOT Spectacles in Chinese Children

CATHAY
Start date: February 5, 2023
Phase: N/A
Study type: Interventional

This is a randomized, controlled, evaluator-blinded, multicenter, two-arm parallel group clinical trial of 12-months duration to evaluate the continued safety and efficacy of Diffusion Optics Technology (DOT) spectacle lenses by comparing to single vision, impact-resistant spectacle lenses in reducing the progression of juvenile myopia in children of Chinese origin.

NCT ID: NCT05562297 Not yet recruiting - Clinical trials for Pancreatic Cancer Stage III

Neoadjuvant/Adjuvant Sintilimab, Nab-paclitaxel, and Gemcitabine for Resectable/Borderline Resectable Pancreatic Cancer

Start date: July 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this research is to investigate the activity and safety of the combination of gemcitabine plus nab-paclitaxel and sintilimab as neoadjuvant therapy in treating patients with resectable and borderline resectable pancreatic cancer. The drugs involved in this study are: - Sintilimab - Nab-paclitaxel - Gemcitabine

NCT ID: NCT05562284 Recruiting - Clinical trials for Central Retinal Artery Occlusion

Safety and Efficacy After Selective Intra-arterial Thrombolysis for Central Retinal Artery Occlusion

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Central retinal artery occlusion (CRAO) is an ophthalmic emergency which leads to devastating visual function defects and poor prognosis. Though traditional conservative treatments are widely used, none of them is proved to be effective. A number of meta-analyses and observational studies indicate intravenous thrombolysis to be beneficial in CRAO. Selective intra-arterial thrombolysis (IAT) introducing rt-PA directly into the ophthalmic circulation by super-selective microcatheterization may reduce the complications such as intracranial and systemic hemorrhage.The residual visual field is significant for patients with CRAO who have poor central visual acuity. Thus, it is clinically significant to study the changes in visual fields in eyes with CRAO.

NCT ID: NCT05562219 Recruiting - Clinical trials for Intermediate Age-Related Macular Degeneration

QA108 Phase II Study in Subjects With Intermediate Age-Related Macular Degeneration

Start date: June 29, 2022
Phase: Phase 2
Study type: Interventional

This is a phase 2, randomized, double-masked, placebo-controlled, multicenter study. To evaluate the efficacy and safety of QA108 granules in the treatment of intermediate age-related macular degeneration.

NCT ID: NCT05562076 Not yet recruiting - Clinical trials for Peripheral Artery Disease

Clinical Study of Focal Implant Used for Lower Extremity Post-angioplasty Dissection

PINTO
Start date: November 2022
Phase: N/A
Study type: Interventional

This is a prospective, multicenter, randomized controlled trail using spot stenting to treat lower extremity post-angioplasty dissection.

NCT ID: NCT05562024 Recruiting - Clinical trials for B7-H3-positive Relapsed/ Refractory Neuroblastoma

TAA06 Injection in the Treatment of Patients With B7-H3-positive Relapsed/ Refractory Neuroblastoma

Start date: December 30, 2022
Phase: Phase 1
Study type: Interventional

Phase I clinical trials are designed as open-label, dose-escalation and dose-expansion clinical studies, the main purpose of which is to explore the tolerability, safety, cytokinetic characteristics and RP2D and preliminary observation of the efficacy of the study drug in subjects with B7-H3-positive relapsed/refractory neuroblastoma.