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NCT ID: NCT05089175 Recruiting - Clinical trials for Pregnancy Complications

The Investigation of the Prediction Model and Prevention Strategy of Serious Pregnancy Complications in Hypertensive Disorders of Pregnancy Based on the Chinese Population

HDP-RPP
Start date: November 30, 2021
Phase:
Study type: Observational [Patient Registry]

1. Evaluation of the efficacy of aspirin in preventing preeclampsia and its serious complications during pregnancy and postpartum. 2. To establish a risk prediction model for severe pregnancy complications in pregnant women with hypertensive disorders of pregnancy.

NCT ID: NCT05088850 Recruiting - Clinical trials for Prediction of Sepsis in Critical Patients

The Early Prediction of Sepsis in ICU

Start date: May 30, 2020
Phase:
Study type: Observational

Sepsis is a vital issue in critical care medicine, and early detection and intervention are key to survival. We aimed to establish an early warning system for sepsis based on a data integration platform that can be implemented in the ICU.

NCT ID: NCT05088733 Recruiting - Clinical trials for Hepatocellular Carcinoma

Yang Yin Fu Zheng Jie Du Therapy in HBV Related Hepatocellular Carcinoma Induced Anemia (YYFZJDTIHBVRHCIA)

Start date: July 1, 2020
Phase: Early Phase 1
Study type: Interventional

Clinical research of Yang Yin Fu Zheng Jie Du therapy in HBV related hepatocellular carcinoma induced anemia. The purpose of this study is to observe the efficacy of routine medical care combined with Yang Yin Fu Zheng Jie Du therapy for patients belong to HBV-HCC induced anemia.

NCT ID: NCT05088226 Recruiting - Clinical trials for Peripheral Blood Stem Cell Transplantation

Ruxolitinib and Chidamide Intensified Bu/CY Conditioning Regimen

Start date: December 1, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of Ruxolitinib and Chidamide intensified conditioning regimen in patients with Acute B cell Lymphoblast leukemia Underwenting Haploidenticl Peripheral blood Stem Cell Transplantation.

NCT ID: NCT05088161 Recruiting - Patients Clinical Trials

Prognostic Biomarkers of Pancreatic Cancer Based on Proteomics Techniques

Start date: May 13, 2021
Phase:
Study type: Observational

In this study, we will use high-throughput proteomics techniques to search for biomarkers of post-operative prognosis of pancreatic cancer in samples of patients who have been diagnosed with pancreatic cancer through bioinformatics analysis.

NCT ID: NCT05088070 Recruiting - Solid Tumor Clinical Trials

Clinical Study of SPH3348 Tablets, a c-Met Inhibitor, in Patients With Advanced Solid Tumors

Start date: July 2, 2020
Phase: Phase 1
Study type: Interventional

This is a phase 1 clinical trial of SPH3348 tablets, a c-Met inhibitor, in patients with advanced solid tumors with c-Met abnormalities. A modified 3 + 3 design was adopted in patients with advanced solid tumors with c-Met abnormalities, with a total of 6 dose groups, in which accelerated dose escalation was adopted for the lowest dose group, and 3 + 3 dose escalation was adopted from the second dose group. The primary objective was to evaluate the safety and tolerability of SPH3348 tablets in patients with advanced solid tumors with c-Met abnormalities.

NCT ID: NCT05088057 Recruiting - Clinical trials for Triple Negative Breast Cancer (TNBC)

Neoadjuvant Camrelizumab Plus Chemotherapy in Triple Negative Breast Cancer

Start date: September 20, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Camrelizumab plus chemotherapy as neoadjuvant therapy and Camrelizumab as adjuvant therapy in participants who have triple negative breast cancer (TNBC).

NCT ID: NCT05087745 Recruiting - Clinical trials for Advanced Solid Tumor

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Start date: December 10, 2021
Phase: Early Phase 1
Study type: Interventional

This study is to investigate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy in patients with advanced solid tumors. Autologous TILs are expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodepletion treatment with hydroxychloroquine(600mg,single-dose) and cyclophosphamide.

NCT ID: NCT05087706 Recruiting - Clinical trials for Salivary Gland Neoplasms

Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer(MAPS)

MAPS
Start date: July 30, 2021
Phase:
Study type: Observational [Patient Registry]

To explore the feasibility, efficacy and safety of determining the treatment regimen based on genomic profiling in patients with locally advanced and advanced salivary gland cancer.

NCT ID: NCT05087589 Recruiting - Clinical trials for Primary Sjögren's Syndrome

Efficacy, Safety and Immunological Evaluation of Tofacitinib in the Treatment of Primary Sjogren's Syndrome

Start date: November 20, 2021
Phase: Phase 2
Study type: Interventional

This study aims to explore the clinical and immunological efficacy of tofacitinib on primary Sjögren's Syndrome