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NCT ID: NCT05711459 Recruiting - Clinical trials for Drug-Induced Acute Liver Injury

Bicyclol in the Treatment of Antineoplastic Drug-induced Liver Injury.

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The clinical trial is designed to evaluate the efficacy of bicyclol for patients with antineoplastic drug-induced liver injury and investigate factors effecting the therapeutic outcome.

NCT ID: NCT05710835 Recruiting - Clinical trials for Catheter Complications

Application Study of Infusing Irritant Medications Through Midline Catheter Based on Real World Study

Start date: December 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to learn about the effect on midline catheter outcomes when infusing irritant medications through midline catheter. The main questions it aims to answer are:Identify the current situation of infusing irritant medications through midline catheter;Explore the effect on midline catheter outcomes when infusing irritant medications through midline catheter;Identify specific medications that affect catheter outcomes.

NCT ID: NCT05710055 Completed - Overweight Clinical Trials

The Efficacy on Overweight With Oral Supplemenation of Probiotics and Prebiotics

Start date: February 6, 2023
Phase: N/A
Study type: Interventional

The goal of this interventional study is to evaluate the efficacy of probiotics with prebiotics on overweight. 200 eligible participants with overweight will be enrolled and randomized to consume four study products for 3 months. Reseachers will compare the four groups to evaluate whether there is significant improvement on overweight for participants in the study product of probiotics with prebiotics.

NCT ID: NCT05709990 Completed - Overactive Bladder Clinical Trials

Efficacy and Safety of High Dose Vitamin D Supplementation for Overactive Bladder Dry in Children

Start date: January 15, 2023
Phase: N/A
Study type: Interventional

This prospective, randomized, 3-arms, parallel-design, controlled clinical trial is conducted to determine whether high dose vitamin D supplementation (combined with standard urotherapy ) improves outcomes, compared with solifenacin (combined with standard urotherapy ) ,and standard urotherapy alone in children with OAB dry.

NCT ID: NCT05709886 Not yet recruiting - Liver Cancer Clinical Trials

A Prospective, Single-arm, Multicenter Clinical Trial of Safety and Effectiveness of EUS-LA for Liver Cancer

Start date: February 28, 2023
Phase: N/A
Study type: Interventional

This trial is a prospective, single-arm, multi-center clinical trial. Four hospitals with national medical trial institution qualifications are selected as clinical trial centers. Qualified participants will receive endoscopic ultrasound-guided laser ablation by LaserPro Diode Laser System according to the routine procedures. The results will be recorded according to the requirements of the primary and secondary efficacy indicators. After then, statistical comparisons of effectiveness and safety of the procedure will be made according to groups.

NCT ID: NCT05709769 Recruiting - Cervical Cancer Clinical Trials

Radiomics-based Malnutrition for Cervical Cancer.

Start date: January 31, 2023
Phase:
Study type: Observational

Loss of skeletal muscle, is one of the most prevalent symptoms of malnutrition, and has been frequently reported as a negative factor in cancer patients at any disease stage. In this study, we are planning to firstly analyze the radiomics features of psoas extracted at the level of the third lumbar vertebra (L3) and then, develop a CT-based radiomics nomogram prediction model for predicting malnutrition based on their Patient-Generated Subjective Global Assessment (PG-SGA) scores in patients with International Federation of Gynecology and Obstetrics (FIGO, 2014 version) stage IB1-IIA2 cervical cancer (CC) who received postoperative radiotherapy/chemoradiotherapy (RT/CRT).

NCT ID: NCT05709288 Recruiting - Hemophilia B Clinical Trials

Gene Therapy for Hemophilia B Patients Aged 12-18 Years Old

Start date: March 23, 2023
Phase: Phase 1
Study type: Interventional

This is a Phase 1, open- label, non- randomized, uncontrolled, single dose pilot study to evaluate the safety, tolerability and efficacy of a single intravenous infusion of BBM-H901 in hemophilia B subjects with ≤2IU/dl residual FIX levels and aged 12-18 years old. BBM-H901 is an adeno-associated viral (AAV) vector designed to drive expression of the human factor IX (hFIX) transgene and raise circulating levels of endogenous FIX.

NCT ID: NCT05709249 Recruiting - Colon Cancer Clinical Trials

Xian-Lian-Jie-Du Optimization Decoction as an Adjuvant Treatment for Prevention of Recurrence of Colon Cancer

Start date: December 1, 2022
Phase: Phase 3
Study type: Interventional

This study is designed as a multi-center, randomized, double-blind, placebo-controlled trial. Subjects in the intervention group will be treated with XLJDOD compound granule. Subjects in the control group will be treated with placebo (XLJDOD mimetic agent).

NCT ID: NCT05709106 Recruiting - Migraine Clinical Trials

A Prospective Real World Study of Rimegepant in the Treatment of Migraine

Start date: February 8, 2023
Phase:
Study type: Observational

The goal of this observational study is to test the effectiveness and safety of Rimegepant in the treatment of migraine patients in real world. The main questions it aims to answer are: - [question 1] the effectiveness and safety of Rimegepant in the acute treatment of migraine - [question 2] the effectiveness and safety of Rimegepant in the long-term treatment of migraine. 1. Participants will be asked to take Rimegepant when they need to treat or prevent a migraine attack. 2. Participants will be asked to record the efficacy data at 0.5, 1, 2, 24, 48h post dose and report any AE to evaluate the effectiveness and safety of Rimegepant in the acute treatment of migraine 3. Participants will be asked to track monthly migraine days and the use of Rimegepant, finish 2 PROs during the follow-ups, report any AE to evaluate the effectiveness and safety of Rimegepant in the long-term treatment of migraine.

NCT ID: NCT05709093 Recruiting - Clinical trials for Myelodysplastic Syndromes(MDS)

A Phase 3 Clinical Study to Evaluate Lemzoparlimab for Injection in Combination With Azacitidine (AZA) Versus AZA Monotherapy in Treatment-naïve Patients With Higher-risk Myelodysplastic Syndrome (MDS)

Start date: March 30, 2023
Phase: Phase 3
Study type: Interventional

This phase3 study is a randomized, controlled, open-label, multicenter study to evaluate the efficacy and safety of Lemzoparlimab for injection in combination with AZA versus AZA monotherapy as first-line therapy in treatment-naïve subjects with intermediate- and high-risk MDS.