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NCT ID: NCT05245058 Recruiting - Clinical trials for HER2-positive Advanced Solid Tumors

SPH5030 Tablets in Subjects With Advanced Her2-positive Solid Tumors

Start date: January 21, 2022
Phase: Early Phase 1
Study type: Interventional

To evaluate the safety and tolerability of SPH5030 tablets in subjects with HER2-positive advanced solid tumors

NCT ID: NCT05245045 Recruiting - Acne Clinical Trials

Efficacy and Safety of STBF Photodynamic Therapy for Moderate and Severe Acne Vulgaris

Start date: February 10, 2022
Phase: N/A
Study type: Interventional

This study is being done to evaluate the efficacy and safety of Shengtaibufen photodynamic therapy (STBF-PDT) for treatment of moderate or severe acne vulgaris.

NCT ID: NCT05244837 Recruiting - Safety Clinical Trials

Predictive Biomarker for Efficacy and Safety of Combination of Chemotherapy and Tislelizumab in NSCLC

Start date: December 22, 2020
Phase: Phase 2
Study type: Interventional

To explore the related biomarkers for safety and efficacy of the combination of chemotherapy and tislelizumab in non-small cell lung cancer

NCT ID: NCT05244642 Recruiting - Clinical trials for Hodgkin Disease Lymphoma

A Phase III Study to Evaluate the Efficacy and Safety of Penpulimab in the Relapsed and Refractory Classical Hodgkin's Lymphoma

Start date: February 15, 2022
Phase: Phase 3
Study type: Interventional

This is an open-label, multicenter, randomized, phase 3 trial to evaluate the efficacy of Penpulimab vs. standard chemotherapy selected by investigator in patients with relapsed or refractory classic Hodgkin's lymphoma.

NCT ID: NCT05244577 Recruiting - Cisplatin Clinical Trials

Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular Cancer

Start date: January 18, 2022
Phase: Phase 3
Study type: Interventional

This study aims to investigate the efficacy and safety of olanzapine combined with fosaprepitant, ondansetron and dexamethasone compared with placebo combined with fosaprepitant, ondansetron and dexamethasone in the prevention of nausea and vomiting in germ-cell tumors receiving 5-day cisplatin chemotherapy

NCT ID: NCT05244551 Recruiting - Solid Tumor Clinical Trials

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors

Start date: June 30, 2022
Phase: Phase 1
Study type: Interventional

This is an open-label phase 1 study with expansion. The study will start with a dose escalation of single-agent ABSK061 administered in repeated 28-day cycles in patients with advanced solid tumors to evaluate safety and tolerability. The expansion part will investigate oral ABSK061 at the recommended dose for expansion (RDE) to further evaluate safety and tolerability among selected tumor types. Preliminary antitumor activity will also be assessed.

NCT ID: NCT05244213 Recruiting - Clinical trials for Non-small Cell Lung Cancer

Neoadjuvant Immunotherapy in EGFR-mutant Localized NSCLC

NEOTIDE
Start date: June 4, 2022
Phase: Phase 2
Study type: Interventional

Phase II, single-arm, open-label single center study that assess clinical feasibility and safety of 3 cycles neoadjuvant Sintilimab plus chemotherapy in EGFR-mutant stage IIB-IIIB NSCLC (excluding N3) followed by optional adjuvant treatment upon investigators' decisions.

NCT ID: NCT05244057 Recruiting - Chronic Hepatitis B Clinical Trials

A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients

Start date: August 23, 2022
Phase: Phase 2
Study type: Interventional

The study is designed to assess efficacy of a finitie treatment in Chronic Hepatitis B patients who had stable treatment of NAs for ≧ 2 years, which is compared hepalatide in combination with Pegylated Interferon + TAF with Pegylated Interferon +TAF. Subjects will be randomly assigned to the hepalatide or placebo groups , 15 subjects in each group . Subjects will receive hepalatide+Pegylated Interferon +TAF treatment for 48 weeks or placebo +PegylatedInterferon +TAF treatment for 48 weeks , Then, stopping all treatments and followed with further 24 weeks follow-up.

NCT ID: NCT05243849 Recruiting - Ischemic Stroke Clinical Trials

Characterization of Retinal Microvascular and FAZ Changes in Ischemic Stroke and Its Different Types

Start date: January 1, 2022
Phase:
Study type: Observational

The study aimed to access the microvascular changes in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) in patients with ischemic stroke and its different types using optical coherence tomography angiography.

NCT ID: NCT05243836 Recruiting - Myopia Clinical Trials

S.T.O.P.® Technology Contact Lenses Versus Dual-focus Contact Lenses for Slowing Down Myopia Progression in Children

Start date: August 4, 2023
Phase: N/A
Study type: Interventional

To compare the rate of myopia progression of contact lenses utilising S.T.O.P.® technology against MiSight® contact lenses.