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NCT ID: NCT05799287 Recruiting - IgA Nephropathy Clinical Trials

A Study of Telitacicept in Patients With Primary IgA Nephropathy

Start date: April 28, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Telitacicept in patients with primary IgA nephropathy.

NCT ID: NCT05799183 Recruiting - Advanced Tumors Clinical Trials

A SHR-1210 BE Study on Healthy Subjects

Start date: July 4, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the bioequivalence of SHR-1210 before and after process changes.

NCT ID: NCT05799040 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Evaluation of the Effectiveness of the Self-developed Pulmonary Lobar Ventilation Detector

Start date: October 26, 2023
Phase:
Study type: Observational

The goal of observational study is to Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector. Participants will use the self-developed pulmonary lobar ventilation detector and the imported Chartis detection system to evaluate the target pulmonary lobar collateral ventilation.

NCT ID: NCT05798845 Recruiting - NSCLC Clinical Trials

The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer

Start date: February 20, 2023
Phase: Phase 2
Study type: Interventional

This randomized phase II trial is to explore the clinical efficacy, safety and feasibility of neoadjuvant immunotherapy plus radiotherapy compared with neoadjuvant immunotherapy plus chemotherapy in operable stage II-IIIA (N+) non small cell lung cancer (NSCLC) and the optimal radiotherapy pattern.

NCT ID: NCT05798819 Not yet recruiting - Clinical trials for Persistent, Recurrent, or Metastatic Cervical Cancer

A Study of GLS-010 Plus Platinum-containing Chemotherapy±Bevacizumab as First-line Treatment for Persistent, Recurrent, or Metastatic Cervical Cancer

Start date: May 1, 2023
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled phase III study to evaluate GLS-010 plus platinum-containing chemotherapy with or without bevacizumab as first-line treatment for persistent, recurrent, or metastatic cervical cancer.

NCT ID: NCT05798793 Recruiting - Clinical trials for Oral Squamous Cell Carcinoma

Neoadjuvant Anti-PD-1 Immunotherapy With Chemotherapy in Resectable Locally Advanced Oral Squamous Cell Carcinoma

NEOPCOSCC
Start date: November 21, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the survival benefit of neoadjuvant anti-PD-1 immunotherapy plus TP chemotherapy compared with TP chemotherapy or up-front surgery in resectable locally advanced oral squamous cell carcinoma.

NCT ID: NCT05798767 Completed - Clinical trials for Cognitive Impairment

Preoperative Cognitive Impairment Predicts Postoperative Delirium

Start date: February 1, 2022
Phase:
Study type: Observational

Preoperative cognitive impairment (PCI) may increase the incidence of postoperative delirium (POD), yet screening for cognitive impairment is rarely performed. This study hypothesized that Mini-Cog for preoperative cognitive impairment screening predicts postoperative delirium. Elderly patients (65 years or older) attending Henan Provincial People's Hospital during the trial period who required elective thoracic surgery were recruited into the study.

NCT ID: NCT05798546 Recruiting - Solid Tumor Clinical Trials

Treatment of Advanced Solid Tumors With Neo-T(GI-NeoT-02)

Start date: September 28, 2022
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to evaluate the safety of Neo-T in the treatment of advanced solid tumors. The secondary objective of this study is to evaluate preliminarily the effect of Neo-T in the treatment of advanced solid tumors.

NCT ID: NCT05798533 Recruiting - Solid Tumor Clinical Trials

Neo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03)

Start date: January 10, 2023
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to evaluate the safety of Neo-T in combination with anti-PD1 in patients with solid tumors. The secondary objective of this study is to evaluate preliminarily the effect of Neo-T in combination with anti-PD1 in patients with solid tumors.

NCT ID: NCT05798416 Completed - Clinical trials for Acute Mountain Sickness

Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude

Start date: February 15, 2023
Phase: N/A
Study type: Interventional

High altitude (>2400 m) is associated with decreased atmosphere pressure leading to hypoxia which in turn impairs exercise capacity and causes acute mountain sickness (AMS). It is noted that adding CO2 might be beneficial to improve hypoxia and exercise performance at high altitude. However, no device is currently available that can supply a constant low dose of CO2 during free movement at high altitude. We have recently invented a portable device which is small and light enough for supplement of low dose CO2 during field exercise at high altitude.