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NCT ID: NCT05870969 Recruiting - Clinical trials for Non-Alcoholic Fatty Liver Disease

Digitalized Surveillance Management for Liver Cancer Risk Population in Improving Eearly Diagnosis Efficancy in Chinese Population (dSEARCH)

dSEARCH
Start date: March 1, 2023
Phase:
Study type: Observational

The goal of this study is to evaluate whether the standardized liver cancer risk stratification management can effectively improve the early diagnosis rate of liver cancer in the targeted risk population in China.

NCT ID: NCT05870917 Recruiting - Clinical trials for Plasma Cell Leukemia

A Study of VRD-based Regimen Combined With CART-ASCT-CART2 Treatment in Patients With Primary Plasma Cell Leukemia

Start date: April 25, 2023
Phase: Phase 2
Study type: Interventional

This is a single-arm, open-label study to evaluate the efficacy and safety of VRD-based Regimen (Bortezomib, Lenalidomide and Dexamethasone) combined with CART-ASCT-CART2 in Chinese patients with newly diagnosed primary plasma cell leukemia.

NCT ID: NCT05870696 Recruiting - Colorectal Adenoma Clinical Trials

the Serum Metabolite Based PrecogColo Dx Test for Advanced Colorectal Neoplasia Screening

Start date: April 30, 2023
Phase:
Study type: Observational

This study is to Evaluate the diagnostic sensitivity of the serum metabolite based PrecogColo Dx test for advanced colorectal neoplasia Screening, including advanced adenoma and colorectal cancer. There are two steps in this study. Firstly, the diagnostic model is established based on tumor-specific and gut-microbiome related serum metabolites. Secondly, the sensitivity, specificity and accuracy of the diagnostic model is evaluated in detecting advanced adenoma and colorectal cancer stages in an independent multi-centered cohort.

NCT ID: NCT05870683 Recruiting - Clinical trials for Helicobacter Pylori Infection

Comparison of Two Dual Therapies in the First-line Treatment of Helicobacter Pylori Infection (SHARE2301)

Start date: May 24, 2023
Phase: N/A
Study type: Interventional

Helicobacter pylori (H. pylori) infection is a common global infectious disease of the gastrointestinal tract. Helicobacter pylori eradication can effectively prevent the development of stomach cancer. Progressive application of dual therapy for the eradication of Helicobacter pylori. Tegoprazan, a Potassium-Competitive Acid Blockers. The efficacy of P-CAB agents represented by vonoprazan in H. pylori eradication therapy has been widely verified.

NCT ID: NCT05870631 Not yet recruiting - Vaccine Reaction Clinical Trials

Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children ( DTaP/DT )

DTaP/DT
Start date: May 2023
Phase: Phase 4
Study type: Interventional

This study is to evaluate the immunogenicity and safety of DTaP or DT given in children aged 6 years.

NCT ID: NCT05870618 Not yet recruiting - Vaccine Reaction Clinical Trials

Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children

DTaP/DT
Start date: May 2023
Phase: Phase 4
Study type: Interventional

This study is to evaluate the immunogenicity and safety of DTaP or DT given in children aged 6 years.

NCT ID: NCT05870514 Recruiting - Critical Illness Clinical Trials

Efficacy and Safety of Fospropofol Disodium Versus Propofol for Deep Sedation in Critically Ill Patients

Start date: June 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of fospropofol disodium for injection compared to propofol for deep sedation in mechanically ventilated ICU patients.

NCT ID: NCT05870475 Recruiting - Polycythemia Vera Clinical Trials

Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV

PV
Start date: May 30, 2023
Phase: Phase 2
Study type: Interventional

Study purpose: To compare the efficacy and safety of pegylated interferon α-2b in combination with ruxolitinib versus pegylated interferon α-2b alone for treating hydroxyurea-resistant or hydroxyurea-intolerant polycythemia vera.

NCT ID: NCT05870436 Recruiting - Asthma Clinical Trials

A Study on the Diagnostic Value of the Methacholine Choline Provocation Test in the Asthmatic Population

Start date: May 19, 2023
Phase:
Study type: Observational

This study was a multicenter, open, observational study and was divided into two stages; Stage I study includes patients with suspected asthma to observe the diagnostic value and safety of Methacholine Choline Provocation Test. All patients clinically evaluated for bronchial provocation testing were included in the stage II study to further validate the diagnostic value and cutoff value of the methacholine choline provocation test.

NCT ID: NCT05870397 Recruiting - Clinical trials for Helicobacter Pylori Eradication

Optimal Recheck Time for Helicobacter Pylori Eradication: A Prospective Randomized Trial

Start date: April 21, 2023
Phase: N/A
Study type: Interventional

Although Urea breath test has been commonly used to recheck the efficiency of Helicobacter pylori eradication, there has been no randomized trials comparing the accuracy of Urea breath test results at different times after eradication. The investigators aim to assess the accuracy and influence factors of post-therapy test at different times and follow up the cut off samples to optimize the best time to recheck.