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NCT ID: NCT05798013 Recruiting - Clinical trials for Head and Neck Vascular Stenosis

Effectiveness of Digital Health Management on Patients With Head and Neck Vascular Stenosis

Start date: August 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of digital health management for intervention on Chinese population with head and neck vascular stenosis.

NCT ID: NCT05797883 Recruiting - Clinical trials for Unresectable or Metastatic Colorectal Cancer

FOLFOX/FOLFIRI Containing Levofolinic Acid (Zuoyu ®) in the Treatment of Unresectable or Metastatic Colorectal Cancer

Start date: August 1, 2022
Phase: Phase 2
Study type: Interventional

To observe and evaluate the efficacy and safety of FOLFOX/FOLFIRI± target-directed regimen containing Levofolinic Acid (Zuoyu ®) in first-line treatment of unresectable or metastatic colorectal cancer

NCT ID: NCT05797623 Recruiting - Clinical trials for Non-severe Aplastic Anemia

Safety and Effectiveness of Trappa Ethanolamine Tablets Combined With Ciclosporin in the Treatment of Primary Treatment of Non-severe Aplastic Anemia

Start date: April 26, 2023
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, double-blind, and open-label, placebo-controlled phase II clinical study. In order to evaluate the effectiveness and safety of trappa ethanolamine tablets combined with ciclosporin in the treatment of patients with non-severe aplastic anemia.

NCT ID: NCT05797610 Recruiting - Clinical trials for Primary IgA Nephropathy

A Study to Evaluate the Efficacy and Safety of RO7434656 in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

IMAGINATION
Start date: August 8, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of RO7434656, a novel Antisense Oligonucleotide (ASO) therapy in participants with primary IgA nephropathy (IgAN) who are at high risk of progressive kidney disease despite optimized supportive care.

NCT ID: NCT05797467 Recruiting - Colorectal Cancer Clinical Trials

Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients

Start date: April 1, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial] is to compare in resectable stage T3-4N2 colorectal cancer. The main question it aims to answer is: whether the use of targeted therapy in combination with adjuvant chemotherapy is associated with improved disease-free survival (DFS) compared to adjuvant chemotherapy alone.

NCT ID: NCT05797454 Recruiting - Breast Cancer Clinical Trials

Efficacy and Accuracy of Combined Localization Versus Single Localization in Non-palpable Breast Cancer

Start date: February 16, 2023
Phase: N/A
Study type: Interventional

The standard method for localizing non-palpable breast cancer is currently preoperative wire-guided localization, its positive margin rate still remains around 20-50%. This study aims to compare the accuracy and efficacy of wire vs. combined breast tissue markers in localizing non-palpable breast cancer.

NCT ID: NCT05797402 Recruiting - Old Age; Debility Clinical Trials

Clinical and Biological Sample Database of Chinese Elderly Patients With Multiple Diseases

Start date: January 1, 2013
Phase:
Study type: Observational

The investigators aim to establish a clinical database and biobank for elderly patients with multiple diseases. The collected data will include demographic information, comorbidity characteristic, FRAIL scale, age-adjusted Charlson comorbidity index, relevant blood tests, the results of imaging examination, prescription of drugs, length of hospital stay, number of overall rehospitalizations and death. With this database, the investigators intend to formulate an individualized treatment strategy for these patients.

NCT ID: NCT05797298 Recruiting - Visual Quality Clinical Trials

Toric Intraocular Lens (IOL) Implantation for Management of Cataracts

Start date: June 1, 2019
Phase:
Study type: Observational

This study included cataract patients who underwent toric intraocular lens (IOL) implantation, which aimed to evaluate the stability and clinical visual quality of toric IOLs.

NCT ID: NCT05797168 Recruiting - Ovarian Cancer Clinical Trials

Phase I/IIa Study for AZD5335 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Solid Tumors

FONTANA
Start date: June 5, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This research is designed to determine if experimental treatment with Antibody-drug conjugate, AZD5335, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced tumors

NCT ID: NCT05797077 Recruiting - Colorectal Cancer Clinical Trials

Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA

Start date: February 20, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to compare in resectable liver metastases colorectal cancer patients.The main question it aims to answer is to investigate whether the progression-free survival (PFS) of resectable colorectal liver metastasis (CRLM) patients with positive ctDNA after surgery is superior with the combination of adjuvant chemotherapy and maintenance therapy compared to adjuvant chemotherapy alone.