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NCT ID: NCT06095206 Recruiting - Infertility Clinical Trials

The Pharmacokinetic and Bioavailability of GenSci094 Before and After a Change in Manufacturing Site

Start date: September 19, 2023
Phase: Phase 1
Study type: Interventional

The bioavailability study is intended to evaluate the pharmacokinetic (PK) characteristics and the bioavailability of the two formulations in humans before and after the change of production site, in order to assess the possible impact of the site change on the pharmacokinetic characteristics of the drug and to clarify whether the two formulations are comparable before and after the change.

NCT ID: NCT06095167 Not yet recruiting - Clinical trials for Nasopharyngeal Carcinoma

Induction Chemotherapy and Immunotherapy Combined Radiotherapy With or Without Concurrent Chemotherapy for Stage III-IVa NPC

Start date: January 1, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare induction chemotherapy (gemcitabine+cisplatin) plus immunotherapy with concurrent chemoradiotherapy (CCRT) or RT alone in patients with stage III-IVa nasopharyngeal carcinoma(NPC), in order to confirm the value of Immunotherapy and concurrent chemotherapy in NPC patients.

NCT ID: NCT06095141 Recruiting - Clinical trials for Pancreatic Adenocarcinoma

Cisplatin to Patients With Pancreatic Cancer and Homologous Recombination Deficiency

PTCA199-6
Start date: December 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of cisplatin based regimen to patients with advanced pancreatic cancer and homologous recombination deficiency.

NCT ID: NCT06095115 Active, not recruiting - Plaque Psoriasis Clinical Trials

A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis

ICONIC-LEAD
Start date: October 12, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is see how effective is JNJ-77242113 in participants with moderate to severe plaque psoriasis.

NCT ID: NCT06094881 Recruiting - Clinical trials for Immune Thrombocytopenia

A Prospective, One-arm and Open Clinical Study of Obinutuzumab in the Treatment of Pediatric Primary Immune Thrombocytopenia (ITP)

Start date: December 2023
Phase: Phase 2
Study type: Interventional

To evaluate the safety and efficacy of Obinutuzumab in the treatment of pediatric primary immune thrombocytopenia in patients who have not responded adequately or relapsed after first-line glucocorticoid treatment.

NCT ID: NCT06094777 Recruiting - Clinical trials for Advanced Solid Tumor

A Study of HY-0102 in Patients With Advanced Solid Tumors

Start date: December 18, 2023
Phase: Phase 1
Study type: Interventional

This is a phase 1 open label multicenter study to evaluate the maximum tolerance, safety, tolerance and PK of HY-0102 administered intravenously (IV) once every two weeks in patients with advanced solid tumors, so as to confirm the recommended phase 2 dose of HY-0102 and obtain the preliminary efficacy information of patients with advanced solid tumors.

NCT ID: NCT06094569 Recruiting - Clinical trials for Endovascular Thrombectomy

Medical Imaging Screening for Posterior-circulation Ischemic Stroke

Start date: June 1, 2019
Phase:
Study type: Observational

Patients with ischemic stroke in the posterior circulation continue to have high rates of mortality and disability, even with aggressive treatment. We wanted to evaluate preoperative imaging to screen patients with a good prognosis from mechanical embolization. We assess the degree of ischemia by defining the pons-midbrain-medulla index (PMMI) and correlate the preoperative PMMI with the clinical prognosis of postoperative patients to verify the validity of PMMI in predicting the clinical prognosis of patients with embolization.

NCT ID: NCT06094556 Recruiting - Clinical trials for Advanced Solid Tumors

An Open Phase I Clinical Trial of SHR-1826 for Injection in Patients With Advanced Solid Tumors

Start date: December 25, 2023
Phase: Phase 1
Study type: Interventional

This is an open, multi-center, dose-escalation/dose-expansion/efficacy expansion phase I clinical study to evaluate the tolerability, safety, PK, and immunogenicity of SHR-1826 in patients with advanced malignant solid tumors, and to preliminatively observe its antitumor efficacy. The whole study was divided into three stages: dose increment, dose extension and therapeutic effect extension.

NCT ID: NCT06094530 Recruiting - Neoplasms Clinical Trials

18F-FAPI-RGD PET/CT in Various Tumor Types

Start date: April 10, 2023
Phase:
Study type: Observational [Patient Registry]

The clinical feasibility of 18F-FAPI-RGD PET/CT will be evaluated in 100 patients with various types of tumor, and the results will be compared with those of 18F-FDG.

NCT ID: NCT06094465 Completed - Clinical trials for Pancreaticoduodenectomy

Learning Curve of Robotic Pancreatoduodenectomy

Start date: April 1, 2020
Phase:
Study type: Observational

A few reports were focused on the RPD learning curve for surgeons with extensive experience in LPD. Therefore, this study aimed to investigate the number of cases required for such surgeons to overcome the learning curve for RPD and to analyze the impact of different phases of the learning curve on perioperative outcomes.