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NCT ID: NCT06437522 Not yet recruiting - Clinical trials for Head and Neck Squamous Cell Carcinoma

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This study is a phase II clinical study to explore the efficacy and safety of BL-B01D1 + PD-1 monoclonal antibody combination therapy in patients with recurrent or metastatic head and neck squamous cell carcinoma (non-nasopharyngeal carcinoma) and other solid tumors.

NCT ID: NCT06437509 Not yet recruiting - Clinical trials for Extensive-stage Small-cell Lung Cancer

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This study is a phase II clinical study to explore the efficacy and safety of BL-B01D1 + PD-1 monoclonal antibody combination therapy in patients with extensive-stage small cell lung cancer.

NCT ID: NCT06437496 Recruiting - Clinical trials for Malignant Neoplasm of Prostate

68Ga-AAZTA-093 PET/CT: First-in-human Study

Start date: April 1, 2024
Phase: Early Phase 1
Study type: Interventional

68Ga-AAZTA-093 is a novel radiotracer targeting prostate-specific membrane antigen (PSMA). In this study, we observed the safety, biodistribution, radiation dosimetry and diagnostic value of 68Ga-AAZTA-093 PET/CT in patients with prostate cancer.

NCT ID: NCT06437457 Completed - Clinical trials for HCC - Hepatocellular Carcinoma

Comparison of Gd-EOB-DTPA-enhanced MRI and Contrast-enhanced Ultrasound for Measuring Tumor Size of Solitary Hepatocellular Carcinoma ≤ 5cm:A Retrospective Study

Start date: January 1, 2019
Phase:
Study type: Observational

Knowing the tumor size before operation is of great significance to the choice of treatment methods of surgeons and the prognosis of patients. In this study, two commonly used imaging methods( CE-MRI/CEUS) were selected to measure and compare the tumor size before operation, in order to determine which measurement method is more accurate.

NCT ID: NCT06437353 Recruiting - Ovarian Cancer Clinical Trials

Surufatinib Combined With Carboplatin/Paclitaxel and Surufatinib Combined With Olaparib as First-line and Maintenance Therapy for Newly Diagnosed High-risk Ovarian Cancer

Start date: May 25, 2024
Phase: Phase 2
Study type: Interventional

The goal of this type of clinical trial study is to evaluate the safety and efficacy of Surufatinib combined with Carboplatin/Paclitaxel and Surufatinib combined with Olaparib as first-line and maintenance therapy for newly diagnosed high-risk ovarian cancer

NCT ID: NCT06437158 Recruiting - Clinical trials for Lymphatic Malformation

Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients

Start date: March 8, 2023
Phase: Phase 2
Study type: Interventional

Bleomycin has nowadays been more and more widely used in the sclerotherapy of LMs, which has been proven to be primarily dose dependent. The investigators aim to compare the efficacy and safety of different concentrations of Bleomycin in the sclerotherapy of LMs for pediatric patients.

NCT ID: NCT06437067 Recruiting - Clinical trials for Acute-On-Chronic Liver Failure

Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal Infection

Start date: March 1, 2023
Phase:
Study type: Observational

The subjects of this study were inpatients with ACLF who were admitted to Tongji Hospital in Wuhan from March 2023 to June 2025. After patients were enrolled, The patient's general information (gender, age, past medical history, etc.), complications (ascites, hepatic encephalopathy, hepatorenal syndrome, gastrointestinal bleeding, etc.), laboratory tests (CRP, PCT, INR, WBC, fungal/bacterial diagnostic tests, etc.), symptoms and signs at the time of infection, and at admission (D1), D4, D7, D14, D21, etc.) were recorded Save the blood separately. The patients were divided into fungal infection group, bacterial infection group and non-infection group according to the infection status after admission.

NCT ID: NCT06437041 Not yet recruiting - Clinical trials for Irritable Bowel Syndrome

Effect of Antibiotic Pretreatment on the Efficacy of WMT in the Treatment of Irritable Bowel Syndrome

Start date: June 2024
Phase: N/A
Study type: Interventional

This is a randomized controlled trial to explore the efficacy of antibiotic pretreatment on the efficacy of WMT in the treatment of Irritable bowel syndrome in adults: a multi-center, randomized, placebo-controlled clinical study

NCT ID: NCT06436989 Enrolling by invitation - Inflammation Clinical Trials

Effect of Temperature Leaching Solution of Disposable Plastic Tableware on Intestinal Health of Adults

Start date: March 24, 2024
Phase: N/A
Study type: Interventional

Studies have shown that disposable plastic tableware will cause harm to human health after heat exposure, which is closely related to the rapid development of modern society and economy and the accelerated pace of life. Most of the existing studies focused on the characterization of micro-nano plastic particles and organic pollutants such as bisphenol A and polycyclic aromatic hydrocarbons produced after thermal exposure of disposable plastic tableware, but did not pay sufficient attention to the potential relationship with individual health effects. In addition; Sporadic animal tests and molecular tests have verified the health hazards of disposable plastic tableware leaching solution. Based on the previous research results, we believe that the leaching solution of disposable plastic tableware at high temperature environment will disturb the intestinal flora structure, affect the intestinal metabolic profile, and produce adverse health outcomes for human intestinal health. This study intends to recruit healthy school students as research objects, and collect urine and stool samples of test subjects, in order to explore the effects of high-temperature leaching solution of disposable plastic tableware on intestinal health of adults.

NCT ID: NCT06436963 Completed - Narrative Medicine Clinical Trials

Exploring the Application of Narrative Medicine Combined With Case-Based Learning in the Standardized Training of General Practice Residents

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This was a prospective, longitudinal, single-center nonrandomized controlled study. A total of 36 first- and second-year general practice residents of Zhejiang University School of Medicine were voluntarily enrolled in the experimental group. The remaining 9 residents served as a control group. The experimental group received narrative medicine training combined with CBL training. The control group received normal CBL training. None of the participants had previously had any training in narrative medicine. Teaching evaluation scores were measured for all subjects at baseline and 1 year after the training.