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NCT ID: NCT06068413 Recruiting - Focal Liver Lesion Clinical Trials

CT Image-assisted Detection Software for Focal Liver Lesions

MRMC
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

To evaluate the safety and effectiveness of the developed and produced CT image-assisted detection software for focal liver lesions before being put into the market.

NCT ID: NCT06068400 Recruiting - Clinical trials for Multiple Myeloma in Relapse

Clinical Study to Evaluate the Safety and Efficacy of CAR-T in the Treatment of Multiple Myeloma

Start date: September 13, 2023
Phase: N/A
Study type: Interventional

This is a single arm, single center clinical study evaluating the safety and efficacy of CAR-T treatment for multiple myeloma.

NCT ID: NCT06068387 Recruiting - Clinical trials for Locally Advanced Cervical Cancer

A Prospective Study on the Prediction Model of Para-aortic Lymph Node Metastasis

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The goal of this prospective single-arm trial is to investigate the accuracy and feasibility of the para-aortic lymph node metastasis prediction model in locally advanced cervical cancer, as well as its impact on patients' prognosis. The main questions it aims to answer are: - Is the para-aortic lymph node metastasis prediction model accurate and feasible? - Whether the para-aortic lymph node metastasis prediction model can affect the prognosis of patients.

NCT ID: NCT06068231 Recruiting - Dental Implant Clinical Trials

A Study of Early Loading of Implants in the Maxillary Anterior Region With Alveolar Bone Defects

Start date: October 3, 2023
Phase: N/A
Study type: Interventional

With the improvement of people's living standards, implant restoration has become an ideal method for partially and completely edentulous patients. Traditional classic implant theory suggests a 3-6 month undisturbed healing period is required before permanent loading can take place. However, this loading plan takes a long time and cannot timely meet the chewing function and aesthetic needs of patients with anterior maxillary tooth loss. Currently, with the continuous improvement of implant design and surface treatment techniques, the speed of implant-bone integration has been increasing, and early loading has gradually become a clinical option. After carefully reviewing the research conducted by domestic and international scholars on early loading of implants in the anterior maxillary region , we found that the cases included in the articles were patients with anterior maxillary tooth loss who did not require simultaneous guided bone regeneration (GBR) surgery. It is well known that patients with anterior maxillary tooth loss often have significant alveolar bone defects. In such cases, GBR techniques are commonly used to repair the bone defect. However, due to the lack of relevant studies, the clinical loading strategies for implant cases with accompanying bone defects are relatively conservative. Clinically, a delayed loading restoration strategy is usually employed, which typically requires a delay of 6 months or even longer. However, delayed loading increases the patient's edentulous time, affects the function and stability of the dental arch, and increases the patient's psychological burden. Therefore, whether an early loading strategy can be used for implant cases with alveolar bone defects in the anterior maxillary region has become a key issue in clinical practice. However, there is few research reported on the timing and effectiveness of early loading of implants in the anterior maxillary region with accompanying alveolar bone defects. This study aims to evaluate the clinical effects of early loading in patients with anterior maxillary single-wall bone defects through a prospective clinical randomized controlled trial.

NCT ID: NCT06068179 Recruiting - Graves' Disease Clinical Trials

Graves' Disease Remission Study: MycoMeth Combo

3M-RGD
Start date: October 16, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

A randomized study to evaluate the efficacy and safety of combining mycophenolate mofetil with methimazole in patients with newly diagnosed Graves' disease.

NCT ID: NCT06067828 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD).

ATHLOS
Start date: October 24, 2023
Phase: Phase 3
Study type: Interventional

This study will investigate the effect of Budesonide, Glycopyrronium, and Formoterol Fumarate (BGF) metered dose inhaler (MDI) compared with Placebo MDI, and Budesonide and Formoterol Fumarate (BFF) MDI on isotime inspiratory capacity (IC) and exercise endurance time.

NCT ID: NCT06067581 Recruiting - Multiple Myeloma Clinical Trials

the Safety and Efficacy of SENL103 Autologous T Cell Injection

Start date: August 21, 2023
Phase: Early Phase 1
Study type: Interventional

To observe the safety and efficacy of SENL103 cells in the treatment of patients with recurrent or refractory plasma cell blood tumors.

NCT ID: NCT06067490 Recruiting - Healthy Volunteers Clinical Trials

A Phase I Study of RC1416 Injection

Start date: July 3, 2023
Phase: Phase 1
Study type: Interventional

This is a phase I study to evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of RC1416 injection via Subcutaneous Administration in Healthy Adult Volunteers.

NCT ID: NCT06067425 Recruiting - Clinical trials for Osteochondrodysplasia

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SAR442501 in Pediatric Participants With Achondroplasia

upreACH-2
Start date: October 10, 2023
Phase: Phase 2
Study type: Interventional

This is a Phase 2, open-label, multicenter, study to evaluate safety, tolerability and efficacy of SAR442501 in children from birth up to 12 years of age with Achondroplasia.

NCT ID: NCT06066905 Recruiting - Clinical trials for Minimal Residual Disease

A Study of Chidamide With AZA in MRD Positive AML After Transplant

Start date: October 26, 2023
Phase: N/A
Study type: Interventional

acute myeloid leukemia (AML) is a malignant tumor of the hematopoietic system with high heterogeneity in cytogenetics and molecular biology.Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is still the primary treatment option for patients with AML and the most effective method for radical treatment of AML.Despite considerable progress in allo-HSCT over the past decade, 30%-40% of patients still relapse, and post-transplant relapse remains the leading cause of death in patients with AML.