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NCT ID: NCT06355479 Completed - Hepatic Cirrhosis Clinical Trials

A Study to Evaluate the Efficacy and Safety of OsrHSA in Patients of Hepatic Cirrhosis With Hypoalbuminemia

Start date: April 10, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to evaluate the efficacy of OsrHSA works to treat hypoalbuminemia in hepatic cirrhosis patients. It will also learn about the safety and immunogenicity of OsrHSA. The main question it aims to answer is whether OsrHSA is effective in elevating the serum albumin level of cirrhotic patients with hypoalbuminemia. Researchers will compare OsrHSA to the positive comparator, plasma-derived HSA (pHSA) to see if OsrHSA presents as non-inferior to pHSA in the indication of hypoalbuminemia in hepatic cirrhosis patients. Participants will be randomized in a 1:1 ratio to receive OsrHSA or HpHSA (20g IV qd) for up to 14 days, following an EOT visit. Follow-up visits will be taken on EOT+7d, EOT+14d, and EOT+30d, respectively.

NCT ID: NCT06355440 Recruiting - Clinical trials for Breast Neoplasm Female

Pilot Study of Financial Navigation Program for Improving Financial Toxicity Among Breast Cancer in China

Start date: March 18, 2024
Phase: N/A
Study type: Interventional

The goal of this pilot study is to access the feasibility and impact of a financial navigation program on improving financial toxicity among patients with breast cancer in China. The main questions it aims to answer are: - Is the intervention feasible and acceptable among participants? - Does the intervention enhance participants' cost-related health literacy? - Does the intervention reduce participants' financial toxicity? Researchers will compare the financial navigation program with usual oncology care to preliminarily evaluate its effectiveness. Participants will receive comprehensive information support, including: - Strategies on patient-physician costs discussion - Skills for inquiring and tracking treatment-related costs - Basic knowledge about health insurance - Guidance on accessing and applying for financial assistance - Suggestions for returning to normal life and work - Strategies for holding a financial-related family meeting

NCT ID: NCT06355258 Recruiting - Clinical trials for COVID 19 Associated Coagulopathy

A Study of the Efficacy of Troxerutin in Preventing Thrombotic Events in COVID-19 Patients

Start date: September 15, 2023
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to learn if troxerutin works to prevent thrombotic events in mild or severe COVID-19 patients. It will also learn about the safety of troxerutin. The main questions it aims to answer are: - Does troxerutin lower the number of thrombotic events in participants? - What medical problems do participants have when taking troxerutin? Researchers will compare troxerutin to a placebo (a look-alike substance that contains no drug) to see if troxerutin works to prevent thrombotic events in COVID-19 patients. Participants will: - Take troxerutin or a placebo every day for 7 days. - Visit the clinic at the first, fourth, seventh and 28th days after enrollment for checkups and tests - Keep a diary of their symptoms and the number of times of thrombotic events, bleeding events and type II HIT-related thrombocytopenia

NCT ID: NCT06355206 Recruiting - Cohort Study Clinical Trials

Natural Course and Therapeutic Effect of Recurrent Acute Pancreatitis

NACRE
Start date: April 22, 2024
Phase:
Study type: Observational

The goal of this observational cohort study is to learn about the etiology, natural course, therapeutic effect and outcome of recurrent acute pancreatitis patients. The main question it aims to answer is: Does endoscopic intervention, surgery or conservative treatment reduce the recurrence of acute pancreatitis? What are the risk factors affecting the recurrence of acute pancreatitis? Patients will be closely followed and clinical information will be recorded.

NCT ID: NCT06355193 Completed - Clinical trials for Treatment of Mild Cases of COVID-19

The Use of Isatidis Root and Forsythia Oral Liquid for the Treatment of Mild Cases of COVID-19: A Trial Clinical Study

Start date: November 1, 2022
Phase: Phase 1
Study type: Interventional

This study has significant implications for research, as it provides a basis for further studies on the antiviral effects of LGLQ Oral Liquid, encouraging more extensive clinical studies in larger populations and diverse age groups to validate these findings. For medical practice, the findings suggest that LGLQ can be considered an alternative treatment option for mild cases of COVID-19, especially in managing symptoms like fatigue, potentially broadening the range of effective treatments available to healthcare practitioners. In terms of policy, the demonstrated efficacy of LGLQ could lead to its inclusion in treatment guidelines for COVID-19 and other viral infections, fostering a more integrated approach combining Western medicine and Traditional Chinese Medicine in the global fight against pandemics. The insights from this study might prompt health policymakers to reassess the potential of herbal formulations in managing and treating infectious diseases and consider them in the development of future healthcare strategies and policies.

NCT ID: NCT06355128 Active, not recruiting - COVID-19 Clinical Trials

A Cross-sectional Study of Ocular Manifestations During the Covid-19 Pandemic in Hubei Province

Start date: January 1, 2024
Phase:
Study type: Observational [Patient Registry]

To investigate the clinical features of ocular manifestations during the novel coronavirus pneumonia pandemic in Hubei at the end of 2022

NCT ID: NCT06355076 Recruiting - Prostate Cancer Clinical Trials

New Urethral Reconstruction in Robot-assisted Laparoscopic Radical Resection

Start date: February 5, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to compare new reconstruction and anastomosis in robot-assisted radical laparoscopic resection It will also understand the possibility of exploring new reconstruction in completely solving patients' postoperative urinary incontinence The main questions it aims to answer are: Is there a significant improvement in urinary control in patients with new reconstruction compared with patients with anastomosis? The researchers compared the new reconstruction with anastomosis in robot-assisted laparoscopic radical resection to see if the new reconstruction improved urinary incontinence after operation. Participants will: The intervention group adopted the new reconstruction proposed by our team; End-to-end anastomosis was performed in non-intervention group.

NCT ID: NCT06354595 Recruiting - Clinical trials for Colorectal Neoplasms

Feasibility Study of Multidimensional Rehabilitation in the Metaverse

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The investigators evaluated and optimized the Metaverse multi-dimensional rehabilitation platform based on the use of the Metaverse multi-dimensional rehabilitation platform by colorectal cancer survivors and their families, and finally launched the Metaverse multi-dimensional rehabilitation platform.

NCT ID: NCT06354569 Recruiting - Clinical trials for Perioperative Respiratory Adverse Events

Risk Factors and Risk Grading Prediction of Perioperative Respiratory Adverse Events in Children

Start date: December 31, 2024
Phase:
Study type: Observational

to explore the risk factors of perioperative respiratory adverse events in children, and to establish a risk prediction model of perioperative respiratory adverse events in children

NCT ID: NCT06354556 Completed - Clinical trials for Obstructive Hypertrophic Cardiomyopathy

Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects

Start date: April 26, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this phase Ⅰ study is to evaluate the effect of oral verapamil tablets on the pharmacokinetics of HRS-1893 in healthy subjects.