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NCT ID: NCT00170963 Completed - Hypertension Clinical Trials

Efficacy and Safety of Valsartan/Amlodipine Combination in Hypertensive Patients Not Controlled With Valsartan Alone

Start date: October 2004
Phase: Phase 3
Study type: Interventional

This study will test the effectiveness and safety of a combination treatment in patients whose blood pressure is not controlled with a single medication

NCT ID: NCT00170885 Completed - Clinical trials for Kidney Transplantation

Everolimus in Combination With Cyclosporine Microemulsion in de Novo Renal Transplant Recipients

Start date: May 2005
Phase: Phase 4
Study type: Interventional

The purpose of the study in de novo renal transplant patients is to evaluate the effect on renal function of an optimized new regimen in comparison with the standard everolimus exposure plus a low-dose cyclosporine microemulsion regimen.

NCT ID: NCT00170846 Completed - Clinical trials for Renal Transplantation

ASCERTAIN: Assessment of Everolimus in Addition to Calcineurin Inhibitor Reduction in the Maintenance of Renal Transplant Recipients

Start date: February 2005
Phase: Phase 4
Study type: Interventional

The study is designed to evaluate whether the initiation of everolimus together with the reduction or discontinuation of calcineurin inhibitors (CNIs) will improve graft function in the maintenance of renal transplant recipients with renal impairment by reducing the progression of chronic allograft nephropathy. The development of atherosclerosis in the native arteries of the patients will also be explored.

NCT ID: NCT00170820 Completed - Clinical trials for Renal Transplantation

Efficacy and Safety of the Switch From Sirolimus to Everolimus in Stable Maintenance Renal Transplant Patients Receiving a Calcineurin Inhibitor Free Regimen

Start date: February 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess if a combination of everolimus, steroids, and mycophenolate mofetil is associated with a better renal function than sirolimus.

NCT ID: NCT00170781 Completed - Clinical trials for Acute Gouty Arthritis

Efficacy and Safety of Lumiracoxib 400 mg Once Daily in Acute Flares of Gout

Start date: June 2005
Phase: Phase 4
Study type: Interventional

This study is designed to develop our understanding of the efficacy and safety of using lumiracoxib in the treatment of patients with acute gout. This is a multi-center, double-blind, randomized, parallel group study comparing a single daily dose of 400 mg lumiracoxib with the established dose of indomethacin 50 mg taken three times a day in terms of efficacy

NCT ID: NCT00170742 Terminated - Clinical trials for Proliferative Diabetic Retinopathy

Study to Assess the Efficacy and Safety of Monthly Octreotide Intramuscular Injections in Patients With Proliferative Diabetic Retinopathy After Lasercoagulation This Study is Not Being Conducted in the United States.

Start date: December 2003
Phase: Phase 3
Study type: Interventional

Phase III study comparing monthly octreotide i.m. in comparison to no additional treatment in patients with proliferative diabetic retinopathy after lasercoagulation.

NCT ID: NCT00168766 Completed - Clinical trials for Relapsing-remitting Multiple Sclerosis

Avonex (Interferon-beta-1a) and Avonex Plus Methylprednisolone for the Treatment of Relapsing-remitting MS

Start date: January 2003
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to determine whether combination treatment (adding methylprednisolone to Avonex) reduces progression of disability over 4 years compared to Avonex alone. The study will also investigate whether combination therapy has any impact on the incidence of relapse and brain atrophy as measured by MRI.

NCT ID: NCT00168701 Completed - Multiple Sclerosis Clinical Trials

Efficacy and Safety of BG00012 in MS

Start date: October 1, 2004
Phase: Phase 2
Study type: Interventional

Determine the efficacy, safety, and tolerability of BG00012 in MS patients.

NCT ID: NCT00168428 Completed - Migraine Disorders Clinical Trials

A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches

Start date: March 2006
Phase: Phase 3
Study type: Interventional

This is a 60 week study including a double-blind phase followed by an open-label phase.

NCT ID: NCT00168077 Completed - Clinical trials for Acquired Coagulation Factor Deficiency

Prothrombin Complex Concentrate for Anticoagulant Reversal

Start date: September 2005
Phase: Phase 3
Study type: Interventional

Patients on oral anticoagulants need rapid reversal of the anticoagulant effect in case of acute bleeding or emergency surgery. Prothrombin Complex Concentrates are known to provide a fast reversal of the anticoagulant effect, with several advantages over alternatives like vitamin K or FFP.The planned clinical Phase III study is designed to provide clinically relevant data on efficacy and safety.