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NCT ID: NCT04944576 Active, not recruiting - Clinical trials for Ankle Injuries and Disorders

Observational Study to Evaluate Safety and Performance of the Total Ankle Prosthesis, EasyMove®

Start date: September 14, 2021
Phase:
Study type: Observational

This study is a post-market clinical follow-up conducted in order to collect long-term data on safety and performance of the EasyMove prosthesis, which is intended to be implanted in case of total ankle replacement, when used in real life conditions according to the instructions for use.

NCT ID: NCT04943042 Active, not recruiting - Clinical trials for Immune Thrombocytopenia

An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP

ADOPT
Start date: February 22, 2022
Phase:
Study type: Observational

This is a multi-center, observational, Phase 4 study in patients with Immune Thrombocytopenia (ITP) designed to describe the real-world effectiveness of Doptelet and assess the patterns of drug utilization to add to the knowledge base regarding the use of Doptelet in routine medical practice. Patients eligible for participation will, as part of their routine medical care, be receiving Doptelet for the treatment of ITP.

NCT ID: NCT04942756 Active, not recruiting - Cancer Clinical Trials

GLYPALCARE STUDY - Multicenter, Randomized Study for Evaluating Continuous Glucose Monitoring (CGM) by Using FreeStyle Libre 2 (FSL2) for Preventing Hyperglycemia/Hypoglycemia Crisis in Advanced Oncological Patients.

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

Cancer patients with known or newly diagnosed (i.e. iatrogenic) Diabetes Mellitus (DM) in Palliative/Supportive Care will be enrolled. Patients will be randomly assigned to one of two groups. Patients included in the first group will monitor glucose levels through Continuous Glucose Monitoring (CGM), using the FreeStyle Libre 2 (FSL2). The second group is represented by the usual standard way for blood glucose (BG) monitoring (lancing device for finger samples). An interim analysis is foreseen when the half of the expected events (hyperglycemic peaks) will be observed. In case the results of interim analysis show superiority of the CGM (FSL2) group patients of the second group will be switched.

NCT ID: NCT04942249 Enrolling by invitation - Covid19 Clinical Trials

Long COVID in Military Organisations

LoCoMo
Start date: May 20, 2021
Phase:
Study type: Observational

A prospective, longitudinal cohort study designed to follow-up on 500 Swiss military personnel who tested in 2020 for SARS-CoV-2 (regardless of whether positive or negative, but with a known test result). Participants are invited to undergo an intensive test battery to evaluate if they suffer COVID-19 sequelae. The testing will include evaluation of several body systems (cardio-vascular, pulmonary, neurological, ophthalmological, psychological and general) and male fertility in a voluntary subgroup. Immune markers and SARS-CoV-2 reinfection rates will also be evaluated. The study hypothesis is that SARS-CoV-2 infection causes a multi-system disease with sequelae detectable in a significant proportion of army recruits after infection with SARS-CoV-2.

NCT ID: NCT04940754 Active, not recruiting - Bone Metastases Clinical Trials

Ankle Arthrodesis Nail for 2-level Pathologic Tibial Fracture

Start date: April 8, 2021
Phase: N/A
Study type: Interventional

Tibial pseudarthrosis in 83 year old patient suffering from pathologic fractures

NCT ID: NCT04939571 Recruiting - Clinical trials for Retinopathy of Prematurity

European Disease Registry on Retinopathy of Prematurity (ROP)

EU-ROP
Start date: August 6, 2021
Phase:
Study type: Observational [Patient Registry]

The EU-ROP registry is a European wide multicenter non-interventional observational registry study intended to run open-ended in as many countries as possible including infants treated for retinopathy of prematurity irrespective of the used treatment modality. The registry is strictly observational; only clinical routine data is collected, no study-specific examinations or interventions are to be performed. The aim of the EU-ROP registry is to collect information on as many patients as possible treated for ROP in Europe. Both the number of study centers as well as the number of patients to be included into the registry are not limited. The primary objective is to describe the typical clinical features of infants with severe ROP, variations in phenotype, and the clinical progression of the disease over time (natural history) in different European countries as well as to study treatment patterns, follow-up patterns, as well as long-term outcomes.

NCT ID: NCT04939545 Completed - Clinical trials for Postoperative Analgesia

Study of Postoperative ICC Analgesia

SPICA
Start date: December 15, 2021
Phase: Phase 3
Study type: Interventional

This study is to examine the analgesic effectiveness of continuous loco-regional analgesic application (ropivacaine) through surgically placed Intercostal Catheter (ICC) and to establish correctly this method as a possible standard of care in the postoperative analgesia after Video-assisted thoracoscopic surgery (VATS) anatomical lung resection.

NCT ID: NCT04939389 Completed - Clinical trials for Status After Knee Surgery

Comparing a Sensor for Movement Assessment With Traditional Clinical Assessment Methods in Patients After Knee Surgery.

MA-KNEE
Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Eight parameters measurable by the sensor "Orthelligent Pro" are compared with traditional measurements based on a goniometer or video taping. The aim is to inform potential users about the distribution of the differences they have to expect when moving from traditional measurement methods to the new sensor. Patients will perform eight corresponding movement exercises at a single study visit.

NCT ID: NCT04939259 Completed - Hearing Loss Clinical Trials

A Comparative Clinical Investigation of Musician's Preference With Hearing Aids

BF007-2101
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

For this study, Bernafon AG will carry out testing with participants with hearing loss to compare a dedicated music program to a general listening program. The Bernafon hearing aids used for the current study are CEmarked and will be released to the market in early 2022. The goal is to determine whether musicians will perceive a difference and prefer the music program over the default listening program in real-life situations. The devices will also be validated for performance before their release to the market.

NCT ID: NCT04939038 Active, not recruiting - Diabetic Foot Ulcer Clinical Trials

Timing of Revascularization in Patients With Diabetic Foot Ulcer and Non-critical Peripheral Artery Disease

DIFU
Start date: January 25, 2022
Phase: N/A
Study type: Interventional

This study investigates whether, compared to standard treatment, immediate restoration of blood flow (revascularization) can reduce complications and improve diabetic foot ulcer healing.