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NCT ID: NCT00604864 Completed - Endometriosis Clinical Trials

Effect of Anti TNFa Upon Deep Endometriosis Associated Pain

Infliximab
Start date: February 2004
Phase: Phase 2
Study type: Interventional

Deep endometriosis associated pain is believed to be caused by inflammation. Anti TNFa has been proved to be an effective treatment for other inflammation related conditions as Crohn's disease Endometriosis is associated with an inflammatory response in the pelvis, which is mediated by a number of cytokines including TNF-α. It has therefore been suggested that infliximab, an anti-TNF-α monoclonal antibody, might relieve pain in affected women.

NCT ID: NCT00604734 Completed - Arthritis Clinical Trials

A Prospective Clinical Study On A Total Hip Resurfacing System

Start date: October 2004
Phase: N/A
Study type: Interventional

This prospective clinical study is to demonstrate the efficacy and safety of ReCap Total Hip Resurfacing System.

NCT ID: NCT00604396 Completed - Clinical trials for Diabetes Mellitus, Type 2

Safety and Efficacy of Insulin Detemir in Combination With OAD in Type 2 Diabetes

Start date: March 2003
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. The aim of this trial is to investigate the safety and efficacy of insulin detemir combined with oral anti-diabetic drugs (OADs) versus insulin NPH combined with oral anti-diabetic drugs (OADs) in Type 2 mellitus not well controlled on current therapy on blood glucose control.

NCT ID: NCT00604214 Completed - Sepsis Clinical Trials

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The purpose of this placebo-controlled study is to determine if drotrecogin alfa (activated) treatment provides significant mortality reduction improvement in patients with septic shock compared with placebo treatment in patients receiving the current standard of care for septic shock. This study will also assess the effectiveness of drotrecogin alfa (activated) in reducing 28-day mortality in patients with septic shock and concomitant severe protein C deficiency.

NCT ID: NCT00603954 Completed - Clinical trials for Hematological Malignancies

Allogeneic HCT With HLA-matched Donors : a Phase II Randomized Study Comparing 2 Nonmyeloablative Conditionings

Start date: January 2008
Phase: Phase 2
Study type: Interventional

The present project aims at comparing two nonmyeloablative regimens currently used in 2 major HCT centers in the US for patients with HLA-matched related or unrelated donor: the one from the Seattle group consisting of 2 Gy TBI with fludarabine (90 mg/m²) versus the one from the Stanford group combining 8 Gy TLI with ATG.

NCT ID: NCT00603252 Completed - Hepatitis B Clinical Trials

Study to Show That the Combined Hepatitis A and B Vaccine is Non-inferior to Monovalent Vaccines in Adults

Start date: January 2008
Phase: Phase 4
Study type: Interventional

This protocol posting describes the booster phase of the study. The objectives & outcome measures of the primary phase are presented in a separate protocol posting (NCT number = NCT00289731).

NCT ID: NCT00602472 Completed - Clinical trials for Diabetes Mellitus, Type 2

BI 1356 (Linagliptin) in Combination With Metformin and a Sulphonylurea in Type 2 Diabetes

Start date: February 2008
Phase: Phase 3
Study type: Interventional

The objective of the current study is to investigate the efficacy, safety and tolerability of BI 1356 (5 mg once daily) compared to placebo given for 24 weeks as add-on therapy to metformin in combination with a sulphonylurea in patients with type 2 diabetes mellitus with insufficient glycaemic control.

NCT ID: NCT00601367 Completed - Clinical trials for Sexual Dysfunctions, Psychological

Flibanserin Evaluation Over 28 Additional Weeks in Hypoactive Sexual Desire Disorder

Start date: January 2008
Phase: Phase 3
Study type: Interventional

Safety profile of flibanserin over 28 additional weeks Distribution of preferred dose regimens

NCT ID: NCT00601172 Completed - Clinical trials for Nausea and Vomiting, Chemotherapy-Induced

A Study Of IV Casopitant For The Prevention Of Chemotherapy Induced Nausea And Vomiting.

Start date: March 10, 2008
Phase: Phase 3
Study type: Interventional

This a Phase III trial designed to determine if IV casopitant plus dexamethasone and ondansetron is more effective in the prevention of vomiting and nausea then dexamethasone and ondansetrone alone following the administration of moderately emetogenic oxaliplatin-based chemotherapy.

NCT ID: NCT00600990 Completed - Clinical trials for Postoperative Nausea and Vomiting

Study Of An NK-1 Anti-Emetic Medication For The Prevention Of Post-Operative Nausea And Vomiting In Female Patients

Start date: December 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness of this medication in preventing nausea and vomiting in female patients at risk for post-operative nausea and vomiting (PONV).