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NCT ID: NCT00837811 Completed - Clinical trials for Rheumatoid Arthritis

An Open Label Extension Study in Participants With Rheumatoid Arthritis

Start date: February 2009
Phase: Phase 2
Study type: Interventional

To evaluate the safety and tolerability of LY2127399 administered as subcutaneous injections for 48 weeks in participants with Rheumatoid Arthritis

NCT ID: NCT00836602 Completed - Atherosclerosis Clinical Trials

Multiple-Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of BMS-779788 in Healthy Subjects

Start date: February 2009
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to evaluate the safety and tolerability of multiple oral doses of BMS-779788 in healthy subjects

NCT ID: NCT00835770 Completed - Clinical trials for Relapsing-Remitting Multiple Sclerosis

BG00012 Monotherapy Safety and Efficacy Extension Study in Multiple Sclerosis (MS)

ENDORSE
Start date: February 3, 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the long-term safety profile of BG00012 (dimethyl fumarate). Secondary objectives of this study are to evaluate the long-term efficacy of BG00012 using clinical endpoints and disability progression, to evaluate further the long-term effects of BG00012 on multiple sclerosis (MS) brain lesions on magnetic resonance imaging (MRI) scans in participants who had MRI scans as part of Studies 109MS301 (NCT00420212) and 109MS302 (NCT00451451) and to evaluate the long-term effects of BG00012 on health economics assessments and the visual function test.

NCT ID: NCT00835419 Completed - Melanoma Clinical Trials

Efficacy Study Of P276-00 In Subjects Of Malignant Melanoma Positive For Cyclin D1 Expression

ENVER
Start date: May 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate efficacy of P276-00 in subjects with advanced malignant melanoma positive for cyclin D1 expression

NCT ID: NCT00833612 Completed - Clinical trials for Acute Myocardial Infarction (AMI)

Counterpulsation Reduces Infarct Size Pre-PCI for AMI

CRISP-AMI
Start date: December 2008
Phase: Phase 4
Study type: Interventional

Subjects with anterior acute STEMI who receive an IABC before primary PCI will have decreased MI size.

NCT ID: NCT00833417 Completed - Clinical trials for Basal Cell Carcinoma

A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) in Patients With Advanced Basal Cell Carcinoma

Start date: February 2009
Phase: Phase 2
Study type: Interventional

This was a Phase II, single-arm, two-cohort multicenter clinical trial evaluating the efficacy and safety of vismodegib (GDC-0449) in patients with advanced basal cell carcinoma. All patients received vismodegib until evidence of progression, intolerable toxicities most probably attributable to vismodegib, or withdrawal from the study.

NCT ID: NCT00833196 Completed - Clinical trials for Idiopathic Cervical Dystonia

Factors Influencing Response to One BoNT-A Injection Cycle in Subjects Suffering From Idiopathic Cervical Dystonia

Start date: February 2009
Phase:
Study type: Observational

A post marketing, international, multicenter, observational, prospective, longitudinal study. The purpose of the study is to describe cervical dystonia sub-types with their injection protocols and response to BoNT-A.

NCT ID: NCT00831844 Completed - Clinical trials for Recurrent Neuroblastoma

Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

Start date: January 2009
Phase: Phase 2
Study type: Interventional

This phase II trial is studying the side effects and how well cixutumumab works in treating patients with relapsed or refractory solid tumors. Monoclonal antibodies, such as cixutumumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them.

NCT ID: NCT00831714 Completed - Clinical trials for Venous Thromboembolism

Xarelto for VTE Prophylaxis After Hip or Knee Arthroplasty

XAMOS
Start date: February 2009
Phase: N/A
Study type: Observational

The main goal is to provide additional information to the risk-benefit assessment of the drug.

NCT ID: NCT00829374 Completed - Alzheimer's Disease Clinical Trials

Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil

CONCERT
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if Dimebon is safe and effective in patients with mild to moderate Alzheimer's disease on Donepezil.