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NCT ID: NCT04405271 Not yet recruiting - COVID-19 Clinical Trials

TAF/FTC for Pre-exposure Prophylaxis of COVID-19 in Healthcare Workers (CoviPrep Study)

Start date: July 31, 2020
Phase: Phase 3
Study type: Interventional

A randomized parallel double-blinded placebo-controlled clinical trial to evaluate the effect of Emtricitabine/Tenofovir alafenamide (FTC/TAF) compared with placebo on the risk of developing SARS-CoV-2 disease (COVID-19) in healthcare workers with high transmission risk in addition to currently recommended control measures.

NCT ID: NCT03981133 Not yet recruiting - Lactation Clinical Trials

Influence of Unrestricted Introduction of Pacifiers on Breastfeeding Duration

Start date: January 2020
Phase: N/A
Study type: Interventional

We will enroll 1010 mother-infant dyads in a randomized trial exploring the effect of distribution of the pacifier during the first days of life on breastfeeding prevalence and duration. .

NCT ID: NCT03542006 Not yet recruiting - Clinical trials for Central Serous Chorioretinopathy

Brinzolamide for the Treatment of Chronic Central Serous Chorioretinopathy

Start date: June 1, 2018
Phase: Phase 2
Study type: Interventional

Examine the efficacy of brinzolamide for the treatment of central serous chorioretinopathy

NCT ID: NCT03138486 Not yet recruiting - Clinical trials for Various Advanced Cancer

A Study of the Effectiveness in Patients With Gastric or Gastroesophageal Junction Cancer With Nivolumab by Itself or in Combination With Ipilimumab and in Patients With Esophageal Cancer With Combination of Nivolumab and Ipilimumab.

CheckMate 648
Start date: June 1, 2017
Phase: Phase 2
Study type: Interventional

The main purpose of this study for patients with gastric or gastroesophageal cancer is to evaluate how well the tumor is responding to treatment with nivolumab by itself, or in combination with ipilimumab. For patients with esophageal cancer, the main purpose is to evaluate how well the tumor is responding to treatment with the combination of nivolumab and ipilimumab.

NCT ID: NCT02963129 Not yet recruiting - Epistaxis Clinical Trials

Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT

Start date: June 2017
Phase: Phase 3
Study type: Interventional

Compare the frequency of epistaxis and quality of life related to nasal bleeding in patients with HHT colonized with sataphylococo before and after being treated with mupirocin ointment.

NCT ID: NCT02399358 Not yet recruiting - Hyponatremia Clinical Trials

Factors Associated With Hyponatremia Induced by High-dose Cyclophosphamide

Start date: December 2015
Phase: N/A
Study type: Observational

Prospoctive cohort of high-dose cyclophosphamide exposed patients. With active estandardize screening of hyponatremia development in the follow up period.

NCT ID: NCT02199015 Not yet recruiting - Cerebral Palsy Clinical Trials

Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy

Andreani1
Start date: June 1, 2025
Phase: N/A
Study type: Interventional

The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected cases of patients with cerebral palsy

NCT ID: NCT01702103 Not yet recruiting - Nasal Obstruction Clinical Trials

Demonstrate the Therapeutic Clinical Equivalence of Two Mometasone Nasal Sprays

PHT-01-12
Start date: October 2012
Phase: Phase 3
Study type: Interventional

Demonstrate the therapeutic clinical equivalence of two mometasone nasal sprays in the relief of the signs and symptoms of perennial allergic rhinitis, in term of changes at week 8 from baseline of Total Nasal Symptom Scores (TNSS).

NCT ID: NCT01664546 Not yet recruiting - Pregnancy Clinical Trials

Study of the Best Blastocyst Post Transfer by aCGH

Start date: September 2012
Phase: N/A
Study type: Observational

An Observational, blind and prospective study of Preimplantational Aneuploidy Screening by aCGH in Trophectoderm Biopsy

NCT ID: NCT01391845 Not yet recruiting - Infertility Clinical Trials

Ulipristal Acetate on Progesterone Levels and Glycodelin-A Endometrial Pattern

Start date: July 2011
Phase: N/A
Study type: Interventional

Controlled ovarian stimulation (COS) for FIV increases progesterone (P) and estradiol (E2) serum levels in supraphysiologic concentrations at the end of follicular phase. Elevated serum P levels leads to an accelerated endometrial maturation which interferes with the dialogue between embryo and endometrium. It has been reported that serum progesterone levels ≥ 1.5 ng/ml on the last day of COS are related to a significant decrease in the ongoing pregnancy rate following IVF cycles. Also, it has been reported a significant alteration in the endometrial gene expression profile related to P elevated levels. Glycodelin-A is an immunomodulatory glycoprotein synthesized by luteal-phase endometrial epithelium and its expression seems to be related to the action of P. Because glycodelin-A has immunosuppressive activity, it may facilitate the process of implantation and the maintenance of pregnancy. It is already know that ulipristal acetate (UPA) decrease serum P levels. The hypothesis of this study is that UPA is been able to modify P serum levels and glycodelin-A endometrial expression pattern on FSH/GnRH Antagonist cycles for FIV.