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NCT ID: NCT00428948 Completed - Clinical trials for Polycystic Kidney Disease, Autosomal Dominant

Tolvaptan Phase 3 Efficacy and Safety Study in ADPKD

TEMPO3/4
Start date: January 2007
Phase: Phase 3
Study type: Interventional

This study's purpose is to evaluate the long-term safety and efficacy of tolvaptan versus placebo in patients with ADPKD.

NCT ID: NCT00428220 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study.

Start date: July 2007
Phase: N/A
Study type: Interventional

This is a study using sunitinib for patients ending treatment on a previous sunitinib malate protocol to continue to receive sunitinib. The patient must have been enrolled in one of the following studies: A6181030, A6181064, A6181078, A6181087, A6181094, A6181107, A6181108, A6181110, A6181111, A6181112, A6181113, A6181120, A6181126 and A6181170. Other Pfizer sponsored sunitinib studies may be included in the future.

NCT ID: NCT00426660 Completed - Clinical trials for Advanced HIV Infection

Expanded Access Program for Maraviroc At Multiple Centers

Start date: February 2007
Phase: Phase 3
Study type: Interventional

To provide access to maraviroc to patients who have limited or no therapeutic treatment options and to collect more safety data in a broader patient population.

NCT ID: NCT00425919 Terminated - Diabetes Mellitus Clinical Trials

Study Evaluating PPM-204 In Subjects With Type 2 Diabetes

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to learn whether PPM-204 has an effect on lowering blood glucose (blood sugar) levels and is safe in treating people with type 2 diabetes.

NCT ID: NCT00425555 Completed - Clinical trials for Cutaneous T-Cell Lymphoma

Study of Oral LBH589 in Adult Patients With Refractory Cutaneous T-Cell Lymphoma

Start date: January 2007
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety and efficacy of LBH489B in adult patients with refractory Cutaneous T-Cell Lymphoma.

NCT ID: NCT00425321 Completed - Clinical trials for Rheumatoid Arthritis

Safety and Effectiveness Study of RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to evaluate the safety and tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to 12 weeks in patients with active Rheumatoid Arthritis despite methotrexate therapy.

NCT ID: NCT00424476 Completed - Clinical trials for Systemic Lupus Erythematosus

A Study of Belimumab in Subjects With Systemic Lupus Erythematosus (SLE)

BLISS-52
Start date: May 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, tolerability, and impact on quality of life of two different doses of belimumab administered in addition to standard therapy in subjects with active, autoantibody-positive systemic lupus erythematosus (SLE) disease.

NCT ID: NCT00424255 Completed - Clinical trials for Neoplasms, Head and Neck

Study Of Adjuvant Lapatinib In High-Risk Head And Neck Cancer Subjects After Surgery

Start date: December 2006
Phase: Phase 3
Study type: Interventional

This is a randomised, double-blind, placebo-controlled, multicentre, global Phase III trial comparing the efficacy of adjuvant oral lapatinib versus placebo in high-risk subjects with head and neck cancer following surgery. Lapatinib or placebo will be administered post-operatively in combination with chemoradiotherapy followed by maintenance with lapatinib or placebo for 1 year. The primary goal is to determine if lapatinib is effective at reducing the recurrence of the disease in these high-risk patients.

NCT ID: NCT00424190 Completed - Clinical trials for Bacterial Infections

Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections

cSSSI
Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of complicated skin infections in adults.

NCT ID: NCT00423891 Completed - Clinical trials for Hepatitis B, Chronic

A Study of Entecavir in Pediatric Patients With Chronic Hepatitis B Virus (HBV)-Infection

Start date: June 30, 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this clinical study is to determine the appropriate doses of entecavir to use in children and adolescents. Safety, tolerability and efficacy will also be studied