Coronary Disease Clinical Trial
Official title:
The Safety and Feasibility of Delivering Xenon to Patients Before and After Coronary Artery Bypass Graft Implantation: a Pilot Study
The aim of this study is to determine whether xenon - as compared to sevoflurane - can be applied safely in patients for general anesthesia before and after CABG implantation.
The study will be conducted by two investigator types: The study enrollment and the
post-anesthesia follow-up will be performed by Investigator I who is blinded to the study
treatment. Investigator II will only perform general anaesthesia for CABG surgery and will
therefore necessarily be unblinded to the treatment conditions.
Patients will be randomly assigned to one of the following study groups. Group 1 (Xenon)
will receive xenon for maintenance of balanced anesthesia for CABG surgery before and after
extracorporal circulation. Group 2 (Sevoflurane) will receive sevoflurane for maintenance of
balanced anesthesia for CABG surgery before and after extracorporal circulation. During
extracorporal circulation, general anesthesia will be maintained intravenously in both
groups.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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