Coronary Disease Undergoing CABG Clinical Trial
Official title:
Randomized Clinical Trials to Compare the Hemodynamic Response During Intubation Between Rigid Laryngoscopy and Track Light in Coronary Patients Undergoing CABG
| Verified date | April 2012 |
| Source | Federal University of Juiz de Fora |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Brazil: Ministry of Health |
| Study type | Interventional |
Opioids provide greater patient comfort during intubation, but are not able to abolish
completely the release adrenergic hormones during the laryngoscopy, which may cause
undesirable hemodynamic changes.
In this study the investigators selected two techniques commonly used for intubation,
laryngoscopy and track light, so the investigators can verify which intubation techniques
provides less hemodynamic changes in coronary patients under standard anesthesia induction.
| Status | Completed |
| Enrollment | 40 |
| Est. completion date | March 2010 |
| Est. primary completion date | March 2010 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 40 Years to 70 Years |
| Eligibility |
Inclusion Criteria: - coronary disease ASA 2 e 3 using beta-blockers Exclusion Criteria: - emergency surgery arrythmia other antiarrythmic drugs |
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Country | Name | City | State |
|---|---|---|---|
| Brazil | National Institute of Cardiology / Ministry of Health | Rio de Janeiro | RJ |
| Lead Sponsor | Collaborator |
|---|---|
| Federal University of Juiz de Fora |
Brazil,
Almeida MC, Martins RS, Martins AL. [Tracheal intubation conditions at 60 seconds in children, adults and elderly patients.]. Rev Bras Anestesiol. 2004 Apr;54(2):204-11. Portuguese. — View Citation
Nishiyama T, Misawa K, Yokoyama T, Hanaoka K. Effects of combining midazolam and barbiturate on the response to tracheal intubation: changes in autonomic nervous system. J Clin Anesth. 2002 Aug;14(5):344-8. — View Citation
Nora FS, Klipel R, Ayala G, Oliveira Filho GR. [Remifentanil: does the infusion regimen make a difference in the prevention of hemodynamic responses to tracheal intubation?]. Rev Bras Anestesiol. 2007 Jun;57(3):247-60. Portuguese. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | hemodynamic response | tracheal intubation with track light release less adrenergic hormones than laryngoscopy intubation | patient prepare (baseline), 1min after induction, 5 min after induction, 1 min after intubation | Yes |