The Relationship Between Cognitive Status and Exercise Capacity, Fatigue Perception in Coronary Artery Patients

Coronary Artery Disease Clinical Trial

Official title:

An Investigation of The Relationship Between Cognitive Status and Exercise Capacity, Fatigue Perception in Coronary Artery Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06246201
• Other study ID #: GO 23/639
• Status: Completed
• Start date: September 1, 2023
• Est. completion date: February 23, 2024

Study information

• Verified date: February 2024
• Source: Hacettepe University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The study aimed to examine the relationship between cognitive status, exercise capacity, and fatigue perception in coronary artery disease patients.

Description:

Exercise training for patients with coronary artery disease is an essential element of multicomponent cardiac rehabilitation. For the successful implementation of exercise-based cardiac rehabilitation programs, adequate cognitive function (e.g. executive function, selective attention, memory) is an important prerequisite. In patients with atherosclerotic coronary artery disease, the presence of coronary microvascular dysfunction as determined by low coronary flow reserve is associated with abnormal cerebral flow hemodynamics and mild but significant impairment in cognitive function. In the literature, there is no study examining the relationship between cognitive level and fatigue perception.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: February 23, 2024
• Est. primary completion date: February 23, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 75 Years

Eligibility

Inclusion Criteria:

• Volunteering to participate in the research

• Being diagnosed with coronary artery disease

• To cooperate with the tests to be performed

• Signing a consent form

Exclusion Criteria:

• Presence of neurological disease that may affect cognitive status

• Presence of clinically unstable cardiac disease

• Left ventricular ejection fraction <30%

• Being diagnosed with end-stage renal failure

• Diagnosed with active myocarditis or pericarditis

• Being diagnosed with rhythm disorder

• Having amputation, peripheral arterial disease, musculoskeletal and/or neurological diseases that will prevent participation in functional capacity tests

• Not volunteering to participate in the study

Related Conditions & MeSH terms

• Coronary Artery Disease
• Fatigue

Locations

Country	Name	City	State
Turkey	Hacettepe University	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Hacettepe University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cognitive State Assessment	Montreal Cognitive Assessment Scale (MoCA) will be used to assess cognitive status.	August 2023-August 2024
Primary	Assessment of Exercise Capacity	Exercise capacity will be evaluated with modified shuttle walking test.	August 2023-August 2024
Primary	Assessment of Perceived Fatigue Severity After Exercise Test	It will be evaluated on the Modified Borg Scale from 0 to 10. 0 means no fatigue. 10 means extremely tired.	August 2023-August 2024
Secondary	Physical Activity Assessment	Physical activity level will be measured with the International Physical Activity Questionnaire (IPAQ). 600 METs (Metabolic Equivalent of Task) min/week means inactive.	August 2023-August 2024