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NCT06338956 Clinical Trial

Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI

Coronary Artery Disease Clinical Trial

— Lipid-PCI  

Official title:
Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06338956
Other study ID # Lipid-PCI
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date January 1, 2024
Est. completion date December 31, 2025

Study information
Verified date March 2024
Source Samsung Medical Center
Contact Ki Hong Choi
Phone 82-2-3410-3419
Email cardiokh@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

For the management of low-density lipoprotein-cholesterol (LDL-C), some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in LDL-C levels. High-intensity or maximally tolerated intensity can be maintained without a target goal. However, the European guideline recommends less than 55 mg/dL of LDL-C after PCI.

Description:

To investigate the Optimal Attained LDL-C Levels in Patients Who Achieved ≥50% LDL-C Reduction After PCI.

Recruitment information / eligibility
Status Recruiting
Enrollment 94189
Est. completion date December 31, 2025
Est. primary completion date December 31, 2024
Accepts healthy volunteers No
Gender All
Age group 19 Years and older
Eligibility Inclusion Criteria: - Patients receiving PCI with health check up before and after PCI within 3 years Exclusion Criteria: - Patients receiving statin before PCI - Patients with liver cirrhosis - Patients with cancer - Patients without prescription of statin - Patients with LDL-C <55 mg/dL before PCI

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• LDL reduction therapy
LDL reduction therapy

Locations
Country Name City State
Korea, Republic of Samsung Medical Center Seoul

Sponsors (1)
Lead Sponsor Collaborator
Samsung Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary MACCE major adverse cardiac and cerebrovascular events 10 years after PCI
Secondary Cardiovascular death death from cardiovascular cause 10 years after PCI
Secondary Spontaneous myocardial infarction MI with hospitalziation 10 years after PCI
Secondary Repeat revascularization additional PCI or CABG 10 years after PCI
Secondary Ischemic stroke Stoke from ischemic cause 10 years after PCI
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