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Effects of CUrcuminoids on Coronary Artery byPass graftIng-related myocarDial Infarction Study — CUPID  

Coronary Artery Bypass Grafting Clinical Trial

Official title:
The Effects of CUrcuminoids on Coronary Artery byPass graftIng-related myocarDial Infarction Study

Clinical Trial Summary

It is well-established that myocardial infarction (MI) associated with coronary artery bypass graft surgery (CABG) predicts the poor outcome. Nevertheless, the cardioprotective therapies to limit myocardial injury after CABG are lacking. Previous studies have shown that curcuminoids suppress pro-inflammatory cytokines during cardiopulmonary bypass surgery and decrease the occurrence of cardiomyocytic apoptosis after cardiac ischemia/reperfusion injury in animal models. The investigators aim to evaluate whether curcuminoids prevent MI after CABG, compared to placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01528514
Study type Interventional
Source Thailand Research Fund
Contact
Status Completed
Phase N/A
Start date September 2009
Completion date December 2012
View Details
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