Lung Tissue Research Consortium

Chronic Obstructive Pulmonary Disease Clinical Trial

— LTRC  

Official title:

Lung Tissue Research Consortium

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02988388
• Other study ID #: LTR01
• Status: Completed
• Start date: February 23, 2017
• Est. completion date: February 21, 2019

Study information

• Verified date: August 2017
• Source: National Heart, Lung, and Blood Institute (NHLBI)
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The LTRC will facilitate histopathological research of pulmonary diseases by collecting lung tissues from donors and preparing and distributing collections of tissue specimens to researchers within and outside the LTRC. Collections of specimens will be linked to individual clinical data appropriate to the particular disease. The primary goal of the LTRC is to identify participants with suspected lung cancer or metastatic disease who are willing to provide informed consent for research use of their specimens and data. Secondarily, the LTRC investigators intend to collect clinical data, limited exposure data, physiologic studies, and radiographic studies from these participants.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 247
• Est. completion date: February 21, 2019
• Est. primary completion date: January 28, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 21 Years and older

Eligibility

Inclusion Criteria:

• Adults ages 21 or older who are undergoing lung surgery for suspected malignancy or metastases.

Exclusion Criteria:

• Diagnosis of cystic fibrosis or pulmonary hypertension.

• Any other condition that, in the judgment of the investigator, precludes participation.

• Failure to obtain written consent.

Related Conditions & MeSH terms

• Chronic Obstructive Pulmonary Disease
• Interstitial Lung Disease
• Lung Diseases
• Lung Diseases, Interstitial
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Intervention

Procedure:
• Lung biopsy/lobectomy
Lung biopsies and lobectomies are not experimental. Participants will undergo a lung biopsy or a lobectomy as part of standard of care.

Locations

Country	Name	City	State
United States	University of Michigan	Ann Arbor	Michigan
United States	Temple University	Philadelphia	Pennsylvania
United States	University of Pittsburgh	Pittsburgh	Pennsylvania
United States	Mayo Clinic Rochester	Rochester	Minnesota

Sponsors (1)

Lead Sponsor	Collaborator
National Heart, Lung, and Blood Institute (NHLBI)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical diagnosis	A final diagnosis of the participant's lung disease will be rendered by the clinical center PI.	Two months following surgery