Chronic Obstructive Pulmonary Disease Clinical Trial
— endothBPCOOfficial title:
Assessment of a Peripheral Endothelial Dysfunction in COPD (Chronic Obstructive Pulmonary Disease)
Verified date | October 2018 |
Source | Hopital Foch |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The aim of the study is to assess the peripheral endothelial function in adult COPD (chronic obstructive pulmonary disease) patients and the relationship between the peripheral endothelial function and the pulmonary function.
Status | Completed |
Enrollment | 137 |
Est. completion date | August 17, 2017 |
Est. primary completion date | July 6, 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 40 Years to 75 Years |
Eligibility |
Inclusion Criteria: - COPD : FEV1/FVC < 70% - Smokers or ex-smokers ( = 10 pack-years) - No COPD exacerbation in the last three months - No history of asthma and no respiratory allergy Exclusion Criteria: - Pregnant or nursing women - Treatment with pulmonary vasodilators - Patients with a significant acute disease. A significant disease is defined as a disease which, in the opinion of the investigator, may influence the results of the trial. |
Country | Name | City | State |
---|---|---|---|
France | Hôpital Saint-Antoine | Paris | |
France | Hôpital Foch | Suresnes |
Lead Sponsor | Collaborator |
---|---|
Hopital Foch |
France,
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* Note: There are 50 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | measure of reactive hyperemia-peripheral artery tone index | measure of reactive hyperemia-peripheral artery tone index | Day 1 | |
Secondary | measure of Forced expiratory flow in one second | measure of Forced expiratory flow in one second | day 1 | |
Secondary | measure of forced vital capacity | measure of forced vital capacity | day 1 | |
Secondary | measure of expiratory flow between 25% and 75% (FEF25-75%). | measure of expiratory flow between 25% and 75% (FEF25-75%). | day 1 |
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