Cognitive Dysfunction in COPD Patients : Role in the Performance of Cognitive-motor Dual Task Situation?

Chronic Obstructive Pulmonary Disease Clinical Trial

— DysCo  

Official title:

Impact of Cognitive Dysfunction in Chronic Obstructive Pulmonary Disease on Performance in Cognitive-motor Dual Task Situation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02493790
• Other study ID #: 5S-DYSCO
• Status: Completed
• Phase: N/A
• First received: June 30, 2015
• Last updated: December 19, 2016
• Start date: October 2014
• Est. completion date: August 2016

Study information

• Verified date: December 2016
• Source: 5 Santé
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Institutional Ethical Committee
• Study type: Observational

Clinical Trial Summary

Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease starting point characterized by multiple systemic effects as cognitive dysfunction. This one seems to have an impact in activity daily living, considered mainly as a cognitive-motor dual task situations. Yet to date, no study has specifically focused in the cognitive-motor performance in patients with COPD or on the effects during a rehabilitation program. The main objective of this work was to evaluate the impact of cognitive dysfunction in COPD, comparing performance between COPD patients and healthy subjects in a single and dual task cognitive-motor situation. The secondary objective was to assess the impact of a rehabilitation program on these performances.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 45
• Est. completion date: August 2016
• Est. primary completion date: June 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 40 Years to 80 Years

Eligibility

Inclusion Criteria:

• Male or female about 40 to 80 years old

• COPD patient (Tiffeneau <70%); stage moderate to severe (Stage 2,3 and 4) with or without oxygen therapy (>15h/day)

• Written and informed consent of the subject

• Authorization to physical activity referring doctor in the clinic

• Comorbidities no dominating

Exclusion Criteria:

• Subject with neurological pathology, cognitive or psychiatric

• Subject with pain and / or plantar injuries

• Subject has a prosthetic knee and / or hip.

• Subject requiring walking aid (cane, walker, etc.)

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Chronic Obstructive Pulmonary Disease
• Cognition Disorders
• Lung Diseases
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Intervention

Other:
• Cognitive and motor performances

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
5 Santé	Groupe 5 Santé

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Variability of Cognitive performances in a single and dual task situations	Cognitive performance were determined by error count and number of substraction during a counting task.	3 months	No
Primary	Variability of motor performances in a single and dual task situations	Motor performance were determined by variability of length and surface of postural condition and by step variability in locomotion condition	3 months	No
Secondary	Effect of rehabilitation program on Cognitive performances in a single and dual task	Comparison before and after rehabilitation program of counting task (number of substraction and error count)	3 months	No
Secondary	Effect of rehabilitation program on motor performances in a single and dual task	Comparison before and after rehabilitation program of variability of length and surface of postural condition and step variability in locomotion condition	3 months	No