Chronic Obstructive Pulmonary Disease Clinical Trial
— RECOPDOfficial title:
Impact of Resistance Training During Hospitalization in COPD Patients: a Randomized and Controlled Trial
The purpose of this study is to determine whether resistance exercise are effective in combating the decline in muscle strength during an exacerbation of Chronic Obstructive Pulmonary Disease (COPD).
Status | Completed |
Enrollment | 34 |
Est. completion date | October 2010 |
Est. primary completion date | December 2009 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: - patients hospitalized for exacerbation of COPD Exclusion Criteria: - patients presenting change in mental status (confusion, lethargy or coma) - persistence or worsening in hypoxemia (PaO2<40mmHg) and/or respiratory acidosis (pH<7.25) despite oxygen supplementation or use of non-invasive ventilation - hemodynamic instability requiring vasoactive drugs - patients transferred to ICU - hospitalization lower than 5 days - diseases that prevented the exercises |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Brazil | University Hospital of sao paulo | São Paulo |
Lead Sponsor | Collaborator |
---|---|
University of Sao Paulo | Fundação de Amparo à Pesquisa do Estado de São Paulo |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The benefits of resistance training during exacerbation of COPD on peripheral muscle strength during hospitalization | The metric used to evaluate the strength gain is given in kilogram (absolute value) and percentage relative to that obtained on the second hospital day | Will be evaluated on the second day of hospitalization, the day of hospital discharge (this time interval must be longer than five days) | Yes |
Secondary | The benefits of resistance training during exacerbation of COPD on physical activity in daily life | The metric used to evaluate the changes will be given in minutes and percentage of total time | Will be evaluated in the third and fifth day of hospitalization and thirty days after discharge | Yes |
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