Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Development of the Partial Pressure of Carbon Dioxide During 6-min Walking Test and at Night in Patients With Chronic Obstructive Pulmonary Disease IV
The aim of this study is to investigate the development of partial pressure of carbon dioxide during the 6-min walking test and during night in Chronic Obstructive Pulmonary Disease (COPD)-patients (GOLD stage IV). Therefore the partial pressure of carbon dioxide, oxygen saturation and the heart rate are registered by a device called "Sentec" during the mentioned periods. In addition a measurement of activity is realised by an activity monitor ("Sensewear").
Status | Completed |
Enrollment | 75 |
Est. completion date | February 2014 |
Est. primary completion date | February 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 30 Years to 75 Years |
Eligibility |
Inclusion Criteria: - COPD IV with and without a respiratory insufficiency - maximal paCO² of 55mmHg at admission (taken at rest by blood gas analysis without LTOT) Exclusion Criteria: - paCO² > 55mmHg - non-invasive ventilation - acute exacerbation |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
Country | Name | City | State |
---|---|---|---|
Germany | Klinikum Berchtesgadener Land | Berchtesgaden |
Lead Sponsor | Collaborator |
---|---|
Klinikum Berchtesgadener Land der Schön-Kliniken |
Germany,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Increase of PaCO2 more than 5mmHg | From time of starting 6-minute walking test until the time of PaCO2-increase of more than 5mmHg assessed up to 6 minutes. | Yes | |
Secondary | Change of PaCO2 | From the beginning of the 6-minute walking test until peak PaCO2, assessed up to 6 minutes | No |
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