Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Nurse Managed Sequential Resistance Then Aerobic Training in COPD
This is a 16 week exercise training program for people with severe to very severe chronic obstructive pulmonary disease (COPD). The purpose of this study is to find out if performing strength training prior to initiating exercise training on a stationary bicycle is associated with greater gains in functional status than bicycle training alone or concurrent bicycle and strength training together.
Status | Completed |
Enrollment | 354 |
Est. completion date | May 2013 |
Est. primary completion date | May 2013 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 46 Years and older |
Eligibility |
Inclusion Criteria: - FEV1/FVC < 70 and FEV1 < 55%, - > 45 years of age, - experience dyspnea with exertion, - stable clinical condition (Stable clinical condition is defined as free of respiratory tract infections for at least two months prior to enrollment, no recent change in the color, consistency, or quantity of sputum, afebrile and no recent change in medical therapy.) Exclusion Criteria: - evidence of restrictive lung disease or asthma, - acute respiratory infection, - taking oral corticosteroids on a regular basis, - >3 exacerbations in the previous year, - currently participating in pulmonary rehabilitation, - the presence of a potentially debilitating disease or the presence of a condition that would make it potentially unsafe to exercise. - We will adhere to the American College of Sports Medicine guidelines and exclude those who do not meet their guidelines for exercise testing and training. - Pregnant women or women who plan to become pregnant during the study. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | University of Illinois at Chicago | Chicago | Illinois |
Lead Sponsor | Collaborator |
---|---|
University of Illinois at Chicago |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | functional capacity for aerobic exercise and for common daily activities | baseline, 16 weeks | No | |
Primary | functional reserve as measured by the reduction in breathlessness and fatigue | baseline, 16 weeks | No | |
Secondary | functional performance and functional capacity utilization as measured by the Functional Performance Inventory and the CHAMPS Physical Activity Scale for Older Adults | baseline, 16 weeks | No |
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