Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
The Effects of Tiotropium on the Cough Reflex in Patients With COPD
Does tiotropium effect the cough reflex in patients with COPD and chronic bronchitis.
Cough Questionnaire
This questionnaire is designed to assess the impact of cough on various aspects of your
life. Read each question carefully and answer by CIRCLING the response that best applies to
you. Please answer ALL questions, as honestly as you can.
1. In the last 2 weeks, have you had chest or stomach pains as a result of your cough? 1 2
3 4 5 6 7 All of the time Most of the time A good bit of time Some time A little of the
time Hardly any time None of the time
2. In the last 2 weeks, have you been bothered by sputum (phlegm) production when you
cough? 1 2 3 4 5 6 7 All of the time Most of the time A good bit of time Some time A
little of the time Hardly any time None of the time
3. In the last 2 weeks, have you been tired because of your cough? 1 2 3 4 5 6 7 All of
the time Most of the time A good bit of time Some time A little of the time Hardly any
time None of the time
4. In the last 2 weeks, have you felt in control of your cough? 1 2 3 4 5 6 7 None of the
time Hardly any time A little of the time Some time A good bit of time Most of the time
All of the time
5. How often during the last 2 weeks have you felt embarrassed by your coughing? 1 2 3 4 5
6 7 All of the time Most of the time A good bit of time Some time A little of the time
Hardly any time None of the time
6. In the last 2 weeks, my cough has made me feel anxious 1 2 3 4 5 6 7 All of the time
Most of the time A good bit of time Some time A little of the time Hardly any time None
of the time
7. In the last 2 weeks, my cough has interfered with my job, or other daily tasks 1 2 3 4
5 6 7 All of the time Most of the time A good bit of time Some time A little of the
time Hardly any time None of the time
8. In the last 2 weeks, I felt that my cough interfered with the overall enjoyment of my
life 1 2 3 4 5 6 7 All of the time Most of the time A good bit of time Some time A
little of the time Hardly any time None of the time
9. In the last 2 weeks, exposure to paints or fumes has made me cough 1 2 3 4 5 6 7 All of
the time Most of the time A good bit of time Some time A little of the time Hardly any
time None of the time
10. In the last 2 weeks, has your cough disturbed your sleep? 1 2 3 4 5 6 7 All of the time
Most of the time A good bit of time Some time A little of the time Hardly any time None
of the time
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05102305 -
A Multi-center,Prospective, OS to Evaluate the Effectiveness of 'NAC' Nebulizer Therapy in COPD (NEWEST)
|
||
| Completed |
NCT01867762 -
An Effectiveness and Safety Study of Inhaled JNJ 49095397 (RV568) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
|
Phase 2 | |
| Recruiting |
NCT05562037 -
Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA
|
N/A | |
| Terminated |
NCT04921332 -
Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD
|
N/A | |
| Completed |
NCT03089515 -
Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust
|
N/A | |
| Completed |
NCT02787863 -
Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology
|
Phase 4 | |
| Recruiting |
NCT05552833 -
Pulmonary Adaptive Responses to HIIT in COPD
|
N/A | |
| Recruiting |
NCT05835492 -
A Pragmatic Real-world Multicentre Observational Research Study to Explore the Clinical and Health Economic Impact of myCOPD
|
||
| Recruiting |
NCT05631132 -
May Noninvasive Mechanical Ventilation (NIV) and/or Continuous Positive Airway Pressure (CPAP) Increase the Bronchoalveolar Lavage (BAL) Salvage in Patients With Pulmonary Diseases?
|
N/A | |
| Completed |
NCT03244137 -
Effects of Pulmonary Rehabilitation on Cognitive Function in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease
|
||
| Not yet recruiting |
NCT03282526 -
Volume Parameters vs Flow Parameters in Assessment of Reversibility in Chronic Obstructive Pulmonary Disease
|
N/A | |
| Completed |
NCT02546700 -
A Study to Evaluate Safety and Efficacy of Lebrikizumab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
|
Phase 2 | |
| Withdrawn |
NCT04446637 -
Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD
|
Phase 3 | |
| Completed |
NCT04535986 -
A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD
|
Phase 3 | |
| Recruiting |
NCT05865184 -
Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD
|
||
| Completed |
NCT03295474 -
Telemonitoring in Pulmonary Rehabilitation: Feasibility and Acceptability of a Remote Pulse Oxymetry System.
|
||
| Completed |
NCT03256695 -
Evaluate the Relationship Between Use of Albuterol Multidose Dry Powder Inhaler With an eModule (eMDPI) and Exacerbations in Participants With Chronic Obstructive Pulmonary Disease (COPD)
|
Phase 3 | |
| Withdrawn |
NCT04042168 -
Implications of Appropriate Use of Inhalers in Chronic Obstructive Pulmonary Disease (COPD)
|
Phase 4 | |
| Completed |
NCT03414541 -
Safety And Efficacy Study Of Orally Administered DS102 In Patients With Chronic Obstructive Pulmonary Disease
|
Phase 2 | |
| Completed |
NCT02552160 -
DETECT-Register DocumEnTation and Evaluation of a COPD Combination Therapy
|