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Clinical Trial Summary

The pre-stage of Chronic Obstructive Pulmonary Disease (Pre-COPD) is challenging to diagnose. However, identifying Pre-COPD is a crucial step in the prevention and management of COPD. Endobronchial optical coherence tomography showed the value of diagnosis in Pre-COPD and COPD in previous researchs.


Clinical Trial Description

We recruited COPD patients (stage I-II, n=15; stage III-IV, n= 15), Pre-COPD (n= 20) and healthy never-smokers (healthy human, n=21). Age,gender,BMI, smoking history, spirometry, chest computed tomography (CT), bronchoscopy and EB-OCT were performed. Inner luminal area (Ai) and airway wall area (Aw) of bronchi which inner perimeter was 10mm, 20mm and 30mm were measured using EB-OCT respectively. By analyzing and studying the above situation, we aim to discover the application value of OCT in Pre-COPD ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06436482
Study type Observational
Source Sichuan Provincial People's Hospital
Contact Guanghong G Zhou, Master
Phone 86-18302880040
Email zhough0526@163.com
Status Recruiting
Phase
Start date March 1, 2023
Completion date July 1, 2024

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