Effects of Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease (COPD)

COPD Clinical Trial

— IMTCO  

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01903772
• Other study ID #: IMTCO
• Secondary ID: Schön Klinik BGL
• Status: Completed
• Phase: N/A
• First received: July 12, 2013
• Last updated: March 1, 2017
• Start date: April 2013
• Est. completion date: February 2017

Study information

• Verified date: March 2017
• Source: Klinikum Berchtesgadener Land der Schön-Kliniken
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 72
• Est. completion date: February 2017
• Est. primary completion date: January 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 90 Years

Eligibility

Inclusion Criteria:

• Patients with COPD

• Eligible to participate in an inpatient pulmonary rehabilitation program of 3 weeks

• Pi,max <60 centimeters of water or <50% of the predicted normal value

Exclusion Criteria:

• Major comorbidities preventing successful participation in an 8 week exercise training intervention

• use of non-invasive ventilation

Related Conditions & MeSH terms

• COPD
• Inspiratory Muscle Weakness
• Muscle Weakness
• Paresis
• Pulmonary Disease, Chronic Obstructive
• Respiratory Aspiration

Intervention

Other:
• Inspiratory Muscle Training

Locations

Country	Name	City	State
Germany	Schön Klinik Berchtesgadener Land	Schönau am Königssee	Bayern

Sponsors (2)

Lead Sponsor	Collaborator
Klinikum Berchtesgadener Land der Schön-Kliniken	Katholieke Universiteit Leuven

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	6-Minute walking distance		change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program
Secondary	exercise capacity (constant work rate test)		change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program
Secondary	maximal inspiratory pressure (PImax)		change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program
Secondary	inspiratory muscle endurance capacity		change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program
Secondary	dyspnea	measured via Borg-scale at rest, during 6-minute walking distance, during constant work rate test at iso-time, during inspiratory muscle endurance capacity test	change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program