COPD Clinical Trial
Official title:
A Pilot Study: Comparing Physiological Parameters and Outcome Variables Using Pressure Support Ventilation Versus Pressure Controlled Ventilation in Patients With Chronic Respiratory Failure
This study is looking at whether there is a difference in outcomes using two different types
of breathing support in those patients who have chronic respiratory failure (patients who
under-breathe).
There is little data to demonstrate which mode of ventilation is better in terms of
physiological outcomes and outcome data relating to patient symptoms.
We hypothesize that one type of breathing support: pressure support ventilation would be
more comfortable for patients as it more closely matches a patient's own respiratory pattern
and and so leads to improved adherence and consequent improvement in quality of life.
Patients with respiratory failure will be randomly assigned to receive either pressure
support ventilation or pressure control ventilation for the first 6 weeks and then
cross-over to receive the mode not previously used for a further 6 weeks. They will have
baseline data recorded and then be followed up after each 6 week block.
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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