Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Arm Training in COPD: Short and Medium Term Effects on Dyspnoea, Health-related Quality of Life, Arm Function and Arm Exercise Capacity.
Patients with chronic lung disease often report shortness of breath when they use their arms
for simple activities of daily living such as dressing, lifting, shaving, bathing and
brushing their hair and teeth. The best type of arm training for these patients is still
unknown.
The objectives of this study are to:
- develop a feasible and safe arm training program (ATP) for these patients;
- examine the effects of this ATP on quality of life, arm function, arm exercise capacity
and symptoms during activities of daily living;
- examine the effects of ATP on breathing responses during arm exercises.
Chronic obstructive pulmonary disease (COPD) is a common condition throughout Canada and the
rest of the world. Patients with COPD often describe of breathlessness that makes it
difficult for them to participate in physical activity. Specifically, patients often report
shortness of breath when they use their arms for simple activities of daily living such as
dressing, lifting and bathing. Exercise training has been shown to reduce breathlessness in
people with COPD. Compared with studies that have looked at the effects of exercise using
the leg muscles, studies that focus on training the arm muscles in people with COPD are
sparse. Although earlier work shows that arm training increases arm exercise capacity, the
effects on other measures such as breathlessness are not clear. Therefore, the objectives of
this study are; (i) to develop a feasible and safe arm training program (ATP) for patients
with COPD based on the best available evidence, (ii) to examine the effectiveness of this
ATP on breathlessness during activities of daily living, health-related quality of life, arm
function and arm exercise capacity, (iii) to examine the physiological mechanisms
underpinning any change in these outcomes in response to the ATP.
Patients with COPD will be assigned by chance to either a treatment or control group. All
patients in both groups will complete the 6-week pulmonary rehabilitation (PR) program that
is well-established at our centre (West Park). During this program all patients will
complete leg exercises, such as walking or cycling, and receive education about how to best
manage their disease. In addition to this PR program, the treatment group will complete a
specific ATP involving overhead arm exercises and free weights. The control group will
undergo a "sham" ATP consisting of finger exercises. Before and after the ATP we will
collect measures of; (i) breathlessness during activities of daily living, fatigue and
quality of life, (ii) arm exercise capacity, (iii) arm function and, (iv) arm muscle force.
During the tests of arm exercise capacity a special machine (breathing-gas analysis system)
will be worn. Measurements will be compared between the treatment and control groups before,
immediately after the ATP and also 3 months after completing the ATP.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
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