Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial
Official title:
Smoking Cessation in Patients With COPD (SMOCC) in General Practice
Background: Smoking cessation is the key element in the treatment of patients with Chronic
Obstructive Pulmonary Disease (COPD). The role of the general practice in assisting these
patients with successful quitting smoking was suboptimal. Therefore we evaluated the
effectiveness of two smoking cessation programs (counseling and nicotine replacement) for
smokers with COPD in routine general practice, one with (CNB) and one without (CN) the
combination with bupropion-SR, compared to usual care (UC) and explored the role of COPD
symptoms in successful smoking cessation.
Method: RCT with 667 patients with COPD, 68 general practices were randomly allocated. The
usual care group (UC) consisted of 148 patients (22 practices), the first intervention group
(counseling plus nicotine replacement (CN) of 243 patients (21 practices) and the second
intervention group of 276 patients (25 practices. Main outcome measure was (biochemically
verified) point prevalence.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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