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Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

Alcohol Drinking Clinical Trial

Official title:
Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

Clinical Trial Summary

This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).

Clinical Trial Description

55 adolescents will receive, in a counterbalanced order, a 10-day course of NAC 1200 mg twice daily and a subsequent 10-day course of matched placebo twice daily, separated by 11 days. Urine and blood samples will be collected at baseline and urine samples again before and after each course of medication treatment. Participants will receive a 1- hour MRI scan at baseline and after each treatment trial. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03238300
Study type Interventional
Source Medical University of South Carolina
Contact
Status Completed
Phase Phase 2
Start date October 16, 2017
Completion date March 1, 2022
View Details
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