Clinical Audit On Management Of Congenital Heart Disease In ACUH

Status Not yet recruiting

Clinical Trial Summary

Congenital Heart Disease (CHD) is the most common birth defect in the United States, affecting approximately 0.8% of live births. Improved treatment strategies and interventions have increased survival such that 85% to 90% of affected children are expected to live well into adulthood, thereby causing a demographic shift in which adults now outnumber children with CHD, and more people with complex CHD are living longer.

Clinical Trial Description

CHD may be defined as an anatomic malformation of the heart or great vessels which occurs during intrauterine development, irrespective of the age at presentation. The cause of most congenital heart defects is still unknown. Many cases of congenital heart disease are multifactorial and result from a combination of genetic predisposition and an environmental stimulus. A small percentage of congenital heart lesions are related to known chromosomal abnormalities, in particular, trisomy 21, 13, and 18 and Turner syndrome. Of all cases of congenital heart disease, 2-4% are associated with known environmental or adverse maternal conditions and teratogenic influences, including maternal diabetes mellitus, phenylketonuria, systemic lupus erythematosus or congenital rubella syndrome; and maternal ingestion of drugs (lithium, ethanol, warfarin, antimetabolites, vitamin A derivatives, anticonvulsant agents). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03850223
Study type	Observational
Source	Assiut University
Contact	Mostafa Shafeek Khalaf, Professor
Phone	+201112110096
Email	mostafa.tawfeek1@med.au.edu.eg
Status	Not yet recruiting
Phase
Start date	March 1, 2020
Completion date	December 1, 2021

View Details

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