Endothelin Blockade in Patients With Single Ventricle Physiology

Status Completed

Clinical Trial Summary

Recent studies have shown beneficial effects of sildenafil in patients with single ventricle congenital heart disease. The purpose of this study is to determine whether Bosentan, a drug with similar effects, will have similar benefit in this patient population.

Clinical Trial Description

Patients enrolled in the study will take Bosentan. Baseline and follow up measurements will be collected then analyzed. ;

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00989911
Study type	Interventional
Source	University of California, Los Angeles
Contact
Status	Completed
Phase	N/A
Start date	May 2010
Completion date	March 2013

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