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Congenital Abnormalities clinical trials

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NCT ID: NCT04763395 Completed - Clinical trials for Liver Function Tests Abnormalities

Liver Function Test Abnormalities in COVID-19

COVID-19
Start date: January 29, 2021
Phase:
Study type: Observational

With the increasing number of COVID-19 infected patients, several studies reported that the liver is the most frequently affected organ after lung damage. The percentage of infected patients who had abnormal levels of transaminases (alanine aminotransferase (ALT) and aspartate aminotransferase (AST)) was about 14.8-53.1%. The elevation in serum bilirubin was mostly mild. Aims of work: - To study liver function tests abnormalities in Egyptian patients who infected with COVID19 - To evaluate if liver function test abnormalities are related to the severity of the Covid19.

NCT ID: NCT04752995 Completed - Deformity of Limb Clinical Trials

Proximal Tibial Osteotomy Osteoclasis In Infantile Genu-Varum

Start date: January 2013
Phase: N/A
Study type: Interventional

Genu-varum is a common problem encountered in pediatric orthopedic. Correction of pathological deformity is mandatory to ensure normal load transfer through the knee. In this study, the investigators describe a new technique of osteotomy osteoclasis in order to evaluate if it is an effective and reliable method in management of infantile genu varum

NCT ID: NCT04732546 Recruiting - Clinical trials for Mullerian Anomaly of Uterus, Nec

Diagnostic, Therapeutic and Reproductive Aspects of Patients With Mullerian Anomalies (MULAN)

MULAN
Start date: January 1, 2000
Phase:
Study type: Observational

The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian anomalies.

NCT ID: NCT04729868 Completed - Forearm Clinical Trials

Ultrasound Guided Infraclavicular Brachial Plexus Block Using Levo-bupivacaine Alone or Combined With Dexmedetomidine for Hand and Forearm Surgeries

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

To evaluate the efficacy of levo-bupivacaine alone and with dexmedetomidine in Ultrasound guided infraclavicular brachial plexus block for hand and forearm surgeries as regard: Onset of sensory and motor blockade. Duration of sensory and motor blockade. Analgesic pain scores using the verbal rating scale (VRS) for pain. Duration of analgesia postoperative complications.

NCT ID: NCT04707456 Active, not recruiting - Clinical trials for First Trimester Pregnancy

Comparative Study of Learning Curve for First Trimester Fetal Anomaly Scan

Start date: June 11, 2020
Phase: N/A
Study type: Interventional

Ultrasound scans during first trimester are more difficult than routine mid-trimester ultrasound scans. Practice guidelines for first trimester fetal ultrasound scans have been provided by the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) since 2013. Using this guidelines, different levels of proficiency operators might have equal ability to complete first trimester ultrasound scans.

NCT ID: NCT04697498 Recruiting - Chronic Pain Clinical Trials

Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations

BBESPB
Start date: December 16, 2020
Phase: N/A
Study type: Interventional

Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain. Development and implementation in clinical practice perioperative intensive care protocols for surgical correction of spinal deformities.

NCT ID: NCT04696874 Completed - Epididymal Cyst Clinical Trials

Spectrum of Epididymis and Vas Deferens Anomalies Among Children With Cryptorchidism

Start date: September 1, 2017
Phase:
Study type: Observational [Patient Registry]

: Data was collected retrospectively from six centers providing care for patients with undescended testicles from September 2017 to February 2019. All patients whose congenital anomalies of the epididymis or vas deferens were discovered incidentally during operative intervention for cryptorchidism and where photographs of the anomalies were taken were included.

NCT ID: NCT04691791 Completed - Clinical trials for Congenital Coronary Artery Abnormality

Italian Registry of Cardiovascular Magnetic Resonance on Congenital Anomalies of the Coronary Arteries (ITACA-Registry)

ITACA
Start date: September 1, 2019
Phase:
Study type: Observational [Patient Registry]

Italian registry of coronary artery abnormalities diagnosed utilizing cardiac magnetic resonance imaging.

NCT ID: NCT04686227 Not yet recruiting - Infertility Clinical Trials

Prevalence of Uterine Malformations in Newly Married Unselected Population

Start date: January 2023
Phase:
Study type: Observational

Uterine malformation is occur due to the abnormal development of Mullerian canal during embryogenesis and it is known that it reduces the fertility and live birth rate and also increases the abortion and preterm birth rate. There are different classification methods have been used for defining the uterine malformations. The most common used classification method in the World is American Society of Reproductive Medicine (ASRM)'s system. In addition European Society of Human Reproduction and Embryology (ESHRE) and European Society for Gynaecological Endoscopy (ESGE) developed a new classification system. ASRM Uterine malformation Classification which is used for diagnosis and treatment of uterine malformations in our clinic is subdivided into 7 titles: 1. Agenesis or Hypoplasia -(a. Vaginal b. Cervical c. Fundal d. Tubal e. Combine) 2. Unicornuate -(a. Communicating Horn b. Non-Communicating Horn c. No Cavity d. No Horn) 3. Uterus Didelphus 4. Bicornuate Uterus-(a. Complete b. Partial) 5. Uterine Septum- (a. Complete b. Partial) 6. Arcuate Uterus 7. Diethylstilboestrol (DES) Related The diagnosis of some of the uterine malformations have been done by using two dimensional (2D) ultrasonography, hysterosalphingography or surgically (laparoscopy or laparotomy) traditionally. A non-invasive procedure is required for the diagnosis of the uterine malformation, which is evaluating both the uterine contour and endometrial cavity. In recent years frequently used three dimensional (3D) ultrasound is a non-invasive and quick diagnostic technique, and also it is sensitive as MRI. In hospital based case control studies, the frequency of uterine malformation was generally around 6%, while it was 8% in infertile patients and 12% in patients with abortion. However, there is a lack of prospective studies investigating the prevalence of uterine anomalies, fertility potential and effects on pregnancy outcomes in unselected patient groups in the literature. Therefore, at the high level evidence, there is no evidence that these anomalies affect fertility and pregnancy outcomes and should be corrected. In this study it was aimed to investigate the effects of uterine malformations on fecundability and pregnancy outcomes by evaluating the uterine morphology with 3D ultrasonography and calling for control purposes at the 1st and 2nd years of newly married women between the ages of 18-40.

NCT ID: NCT04683250 Recruiting - Clinical trials for RET-altered Solid Tumors

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

(MARGARET)
Start date: December 16, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Phase 1 and 2 trial to study the safety, pharmacokinetics, and efficacy of TAS0953/HM06 in patients with advanced solid tumors with RET gene abnormalities. Phase 1 aims to determine the Maximum Tolerated Dose (MTD) and identify the Recommended Phase 2 Dose (RP2D) to be used in phase 2.