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Computed Tomography clinical trials

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NCT ID: NCT04577495 Completed - Thymoma Clinical Trials

Prognostic Factors in Patients Submitted to Surgical Treatment for Thymoma

Start date: January 2005
Phase:
Study type: Observational

Thymoma is the most common primary tumor of the anterior mediastinum. Complete surgical resection is the mainstay of treatment of these tumors. The staging and histological classification of thymoma is still a matter of discussion. Preoperative computed tomography (CT) scan parameters that correlate with histology, stage and prognosis also still have to be completely assessed. The aim of this study is to evaluate the potential association between clinical, radiologic and pathologic characteristics in patients submitted to surgical treatment for thymoma, assessing their prognostic value. Data of patients submitted to surgical resection for pathologically proven thymoma at our Department of Thoracic Surgery between January 2005 and December 2015 will be retrospectively reviewed. The correlation of preoperative CT scan features, histological and pathological characteristics of thymomas will be evaluated, assessing the prognostic role of these factors.

NCT ID: NCT04577105 Completed - Covid19 Clinical Trials

Risk Factors and Computed Tomography Findings in COVID-19.

Start date: April 1, 2020
Phase:
Study type: Observational

In the SARS-CoV2 pandemic, imaging studies proved its diagnostic utility to determine the severity of lung involvement. Computed tomography (CT) is a state-of-the-art study proven to be a highly sensitive diagnostic test complemented by RT-PCR testing to determine the disease and the degree of severity. In March 2020, the Dutch Society of Radiology developed a standardized assessment scheme for COVID-19 lung disease, called CO-RADS. This system proposes a level of suspicion of pulmonary involvement of COVID-19, based on the simple chest tomography findings. The level of suspicion ranges from very low (CO-RADS 1) to very high (CO-RADS 5), with two additional categories involving a technically deficient study (CO-RADS 0) and a positive RT-PCR test for SARS -CoV-2 known before tomography (CO-RADS 6). For its part, acute respiratory damage secondary to SARS-COV2 pneumonia causes acute respiratory distress syndrome, which warrants immediate medical attention. During the evaluation and triage of patients with suspected or confirmed SARS-COV2 infection, it is a challenge for health personnel given that the severity and clinical presentation is highly variable. The patient's risk stratification is carried out using previously established and validated risk scales and is a fundamental tool for making clinical decisions. Some of the risk indices and scales have been developed and used in the pandemic epicenters, such as China and Europe. Useful for the clinician is the national early warning scale (NEWS 2), severe disease risk assessment score (COVID-GRAM), the rapid severity index for COVID-19 (qCSI), evaluation score of Modified sequential organ failure (mSOFA), the sepsis-induced coagulopathy score (SIC), the ROX index as a predictor of success to the high-flow nasal cannula. The evaluation of the risk of thrombotic complications such as the Padua risk, of cardiac complications such as QT segment prolongation, through the Tisdale risk score. Risk stratification is essential in the current COVID-19 pandemic situation; upon admission, the clinician will discern if the patient requires in-hospital medical treatment, the risk of severe disease, and progression to assisted mechanical ventilation. This work aims to establish whether the severity of the findings identified by cardiac tomography upon admission and the risk established by the different established prognostic indices.

NCT ID: NCT04497311 Recruiting - Covid19 Clinical Trials

Tomographic Findings in COVID-19 and Influenza

TOMOCOVIDMX
Start date: June 15, 2020
Phase:
Study type: Observational

The investigators decided to conduct a longitudinal study that compares the pulmonary tomographic patterns found in patients with viral pneumonia (i.e. influenza H1N1 and SARS-CoV-2) at a regional hospital. The primary aim of this study is to compare the radiological patterns found in patients with COVID-19 and influenza H1N1. The secondary aims of this study will assess the association between the radiological CT pattern and the need for invasive mechanical ventilation and mortality within the first 28 days of intensive care unit admission.

NCT ID: NCT04337164 Completed - Regional Anesthesia Clinical Trials

Radiological Study of PENG Block Depth

Tomo-PENG
Start date: April 8, 2020
Phase:
Study type: Observational

This study evaluates the depth of anatomical landmarks required in regional anaesthesia to perform either Femoral Nerve Block or PENG Block. Measures will be performed on abdominal and pelvic computed tomography as part of daily routine patient care.

NCT ID: NCT03992833 Recruiting - Lung Neoplasms Clinical Trials

Methods of Computed Tomography Screening and Management of Lung Cancer

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

European lung cancer screening studies using computed tomography (CT) have shown that a management protocol based on measuring lung nodule volume and volume doubling time (VDT) is more specific for early lung cancer detection than a diameter-based protocol. However, whether this also applies to a Chinese population is unclear. The aim of this study is to compare the diagnostic performance of a volume-based protocol with a diameter-based protocol for lung cancer detection and optimize the nodule management criteria for a Chinese population.

NCT ID: NCT03917199 Completed - Clinical trials for Coronary Artery Disease

Utility of Regadenoson Low-dose Dynamic Computed Tomography for Myocardial Perfusion Assesment (ULYSSES Study).

ULYSSES
Start date: November 2016
Phase:
Study type: Observational

The ULYSSES study is a single-center, prospective study aimed at evaluation of myocardial ischemia using regadenoson low-dose dynamic computed tomography myocardial perfusion imaging (CTP) in patients diagnosed with intermediate coronary artery stenoses in referrence to the magnetic resonance myocardial perfusion imaging (MR MPI).

NCT ID: NCT03913065 Completed - Computed Tomography Clinical Trials

Head Computed Tomography for Predicting Neurological Outcome After Cardiac Arrest

Start date: November 18, 2017
Phase:
Study type: Observational [Patient Registry]

The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) joint guidelines for post-resuscitation care recommend a multimodal approach to prognostication of neurological outcome. However, head computed tomography (CT) which is commonly used for predicting long-term neurological outcome after cardiac arrest has not yet been examined prospectively in a clinical trial. The primary purpose of the TTM-2 CT-substudy is to prospectively investigate and compare various methods of diagnosing generalized oedema on CT after cardiac arrest and it´s ability to predict long-term neurological outcome.

NCT ID: NCT03894423 Recruiting - Clinical trials for Coronary Artery Bypass

Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery

Start date: May 1, 2019
Phase:
Study type: Observational

Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.

NCT ID: NCT03875469 Completed - Computed Tomography Clinical Trials

Study to Test the Usability of a New Injector to Administer Contrast Media Into Humans for Diagnostic Purposes

PERCENT
Start date: June 21, 2019
Phase: N/A
Study type: Interventional

This study investigates if a new medical device, which injects contrast media and flushing solution into humans to increase the visibility of images taken of the human body for diagnostic purposes, is easier to handle, quicker and cheaper than an older injector.

NCT ID: NCT03776435 Recruiting - Appendicitis Clinical Trials

CT Carcinogenic Risk in Patients With Appendicitis

Start date: January 15, 2018
Phase:
Study type: Observational

The purpose of this study is to compare the incidence rate of leukemia between CT-exposed and CT-unexposed group in patients who underwent appendectomy in South Korea.