Three Regimens of Ketamine Infusion in Complex Regional Pain Syndrome

Status Recruiting

Clinical Trial Summary

To evaluate the efficacy of three regimens of sub anesthetic dose of ketamine infusion in relieving chronic refractory pain in patients with complex regional pain syndrome

Clinical Trial Description

Ketamine N-methyl-D-aspartate (NMDA) receptor blocker that has recently been studied for its analgesic effect is a phencyclidine or phenyl cyclohexyl piperidine (PCP) derivative that initially became commercially available for human use in 1970 as a rapid-acting intravenous (IV) anesthetic. It is currently classified by the Food and Drug Administration (FDA) as an anesthetic induction agent in doses ranging from 1 to 4.5 mg/kg. Ketamine has proven to be a desirable drug, despite of its induction dissociative effects and abuse potential. It is favorable due to its short half-life and lack of clinically significant respiratory depression. In addition to its anesthetic effects, ketamine has analgesic, anti-inflammatory, and antidepressant activities. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05997134
Study type	Interventional
Source	Tanta University
Contact
Status	Recruiting
Phase	Phase 4
Start date	August 30, 2023
Completion date	September 1, 2024

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