Complex Congenital Heart Disease Clinical Trial
An injury of haematosis in post ischemic chronic heart failure limits the clinic tolerance.
There is a correlation between injury of pulmonary diffusing, chronic heart failure intensity
and aerobic physic ability evaluated by an heart-rate maximal exercise tolerance test (VO2
max). This injury is a new follow-up parameter of cardiac function for the adult.
The nature of damage (vascular or membrane) can be determined by the measure of double
pulmonary diffusing capacity to carbon monoxide (CO) associated to nitric oxide (NO).
Today, in chronic heart failure consecutive to a congenital heart disease, there is no data
on evolution of membrane and capillar factors.It is impossible to predict if membrane damage
will be the best factor correlated to the VO2max in patients suffering from complex
congenital heart disease.
Assessing these parameters could be an comparative evaluation of heart-rate exercise
tolerance test with VO2max and an early control of his damage without risks related to
heart-rate maximal exercise and independently of age, sex, hemoglobin, type of heart
disease.These results would have an early prognostic value that would permit to refine the
follow-up and the treatment.
The main objective of this trial is to assess the statistic correlation between the membrane
injury of alveolar-capillary diffusing at rest and aerobic physic ability restriction in
children and adults suffering from complex congenital heart disease.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05943275 -
Magnetic Sensor Validation of Hemodynamic Non-invasive Measurements Pressure During Cardiac Catheterization
|
N/A | |
| Completed |
NCT04810013 -
Noninvasive Measurement of the Cerebral Autoregulation in Neonates and Infants With Complex Congenital Heart Disease
|
||
| Not yet recruiting |
NCT05914103 -
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in the Correction of Complex Congenital Heart Disease
|
N/A | |
| Recruiting |
NCT06149806 -
National Registry of Adult Heart Failure Patients With Complex Congenital Heart Disease: Systemic Right Ventricle and Single Ventricle Treated With Sacubitril/Valsartan
|
||
| Recruiting |
NCT04733378 -
Impact of Surgical Timing on the Neurodevelopmental Prognosis of Newborns With Complex Congenital Heart Disease
|
N/A | |
| Recruiting |
NCT05767385 -
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
|
Phase 2/Phase 3 |