Colorectal Cancer Clinical Trial
Official title:
A Pilot Phase I/II Trial of Enteral Wallstents for Colonic Obstruction in the Setting of Malignancy
RATIONALE: The use of endoscopy to place a metal stent in the large intestine is less
invasive than surgery for treating cancer-related bowel obstruction and may have fewer side
effects and improve recovery.
PURPOSE: Phase I/II trial to study the effectiveness of endoscopic placement of a metal
stent in treating patients who have cancer-related bowel obstruction.
OBJECTIVES:
- Determine the objective response and clinical outcome in patients with colonic
obstruction secondary to malignancy treated with enteral Wallstents.
- Evaluate the efficacy and safety of this treatment in these patients.
- Evaluate the quality of life of these patients after enteral Wallstent placement.
OUTLINE: All patient undergo a colonoscopy, followed by placement of an enteral Wallstent
through an endoscope under fluoroscopic guidance into the large intestine.
Quality of life is assessed at 48 hours and 6 months after the procedure.
Patients are followed at 48 hours, 30 days, 6 months, and then yearly thereafter until
death.
PROJECTED ACCRUAL: A total of 20 patients will be accrued for this study.
;
Primary Purpose: Supportive Care
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