Cognitive Impairment Clinical Trial
Official title:
Observational Study of Cerebral Oxygenation and Spinal Anaesthesia in Elderly Patients With Hip Fracture
The aim of this study is to observe how the hemodynamic changes induced by spinal blockade affect cerebral oxygenation. Elderly patients are very frail. Hypotension is very frequent during spinal anaesthesia. Bradycardia is other side effect of regional anaesthesia affecting cardiac output and cerebral blood flow. These complications of spinal anaesthesia could decline cognitive function. In this way a non invasive monitoring technique as cerebral oximetry is useful for the safety of anesthetic procedure.
Patients aged 70 years old with hip fracture presenting for surgical repair under
intrathecal anaesthesia performed with bupivacaine or L bupivacaine (dose 7 - 9 mg).
Preoperative haemoglobin and drugs consumption are registered. All patients receive
supplemental oxygen during surgery. Cerebral oximetry, blood pressure, heart rate and oxygen
arterial saturation are measured. Level and duration of sensory and motor block are
registered. The study observes if there is any correlation between cerebral oximetry and
these hemodynamic parameters.
The investigators also observe if there is any correlation between cerebral oximetry and
cognitive function evaluated pre and postoperatively by SPMSQ test.
Postoperative SPMSQ test will be performed on the 5th postoperative day and the
complications registered.Patients will be followed for the duration of acute hospital stay.
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Observational Model: Cohort, Time Perspective: Prospective
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