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GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration

Cocaine Dependence Clinical Trial

Official title:
GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration

Clinical Trial Summary

The investigators plan to explore the effects of acute pre-treatment with the glucagon like peptide-1 (GLP-1) agonist, exenatide versus placebo, on the subjective (e.g., euphoric) and behavioral effects (e.g., self-administration) of cocaine in experienced, non-treatment seeking users of the drug. Additionally, the investigators plan to explore the effects of sub-chronic (5-day) treatment with exenatide as compared to placebo on the subjective (e.g., euphoric) and behavioral (self-administration) effects of cocaine in experienced, non-treatment seeking users of the drug.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02302976
Study type Interventional
Source Yale University
Contact
Status Completed
Phase Phase 1
Start date November 2014
Completion date August 1, 2018
View Details
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