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Clinical Trial Summary

Patients with hepatic cirrhosis and previous variceal bleeding will be randomly assigned to use propranolol or carvedilol. After 8 weeks, rosuvastatin or placebo will be blindly added to nonresponders (HVPG measurement > 12mmHg) for another 8 weeks and hemodynamic response will be assessed again.

Surrogate serum markers of portal hypertension will be evaluated and correlated to HVPG values and to its variations.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03720067
Study type Interventional
Source Universidade Federal do Rio de Janeiro
Contact Guilherme FM Rezende, MD, PhD
Phone (5521)999976292
Email guimottarezende@gmail.com
Status Recruiting
Phase Phase 2/Phase 3
Start date January 25, 2019
Completion date December 20, 2022

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