Chronic Periodontitis Clinical Trial
Official title:
Clinical Efficacy of Subgingivally Delivered 0.75% Boric Acid Gel As An Adjunct to Mechanotherapy in Chronic Periodontitis: A Randomized Controlled Clinical Trial
The purpose of the present study was to evaluate the effects of subgingival delivery of boric acid gel as an adjunct to scaling and root planing in chronic periodontitis (CP) patients.
Background: The purpose of this double-masked, randomized, controlled clinical trial was to
evaluate the effects of subgingival delivery of boric acid gel as an adjunct to scaling and
root planing (SRP) on clinical and radiographic parameters and compare this method with SRP
plus placebo gel alone in with chronic periodontitis (CP) patients.
Methods: Thirty nine systemically healthy patients with CP are included in this study. They
were divided into two groups: 1) SRP + 0.75% Boric acid gel (BA group); 2) SRP + Placebo gel
(Placebo group). At baseline, 3 month, and 6 months after treatment, clinical measurements,
including plaque index (PI), modified sulcus bleeding index (mSBI), probing depth (PD),
clinical attachment level (CAL) and radiographic parameters intrabony defect depth (IBD),
percentage change in radiographic defect depth reduction (DDR%) were assessed.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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