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The Link Between Periodontitis, Smoking and Oral Cancer

Chronic Periodontitis Clinical Trial

Official title:
Analysis of the Link Between Periodontitis, Smoking and Oral Cancer: Cohort Study

Clinical Trial Summary

Periodontitis is a widely prevalent disease worldwide that has serious public health consequences. Its prognosis includes tooth loss and edentulism, a condition that negatively affects chewing causing functional disability; and esthetics causing social impairment. Consequently, periodontitis may end up causing marked impairment of the quality of life of the affected patients, impairment of general health and increasing the dental care costs significantly. Changes in the oral mucosa arise by primary products resulting from tissue breakdown due to gingivitis. It then triggers the host cells to produce proteinases that mediate loss of marginal periodontal ligaments, apical migration of the junctional epithelium and apical spread of bacterial biofilm. Therefore, this research aims to identify the risk of smoking to both periodontitis and oral cancer, and the risk of periodontitis to oral cancer.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04047212
Study type Observational
Source Cairo University
Contact Ayat Gamal-AbdelNaser
Phone 01001874257
Email ayat.gamal@dentistry.cu.edu.eg
Status Not yet recruiting
Phase
Start date August 12, 2021
Completion date January 30, 2032
View Details
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