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Clinical Trial Summary

The purpose of this study is to evaluate the clinical efficacy of a probiotic lozenge containing Limosilactobacillus reuteri as an adjunct to the periodontal non-surgical treatment of patients with stage II, grade A, B and C, generalized periodontitis.


Clinical Trial Description

The main purpose of this study is to assess the effect on disease progression of the probiotic Limosilactobacillus reuteri as an adjunct in the non-surgical periodontal treatment in patients with stage II, grade A, B and C, generalized periodontitis: evaluated by Bleeding on Probing (BoP) - Lindhe, 1972. The secondary purpose is to evaluate the effect of this probiotic on the values of Plaque Index (PI) - Silness & Löe, 1964; Gingival Index (GI) - Löe & Silness, 1963; Probing Pocket Depth (PPD), Clinical Attachment Level (CAL) - Ramfjord, 1959, when compared to a negative control product. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05734274
Study type Interventional
Source Universidade do Porto
Contact André Marques, MDent
Phone +351965074955
Email andrecnbmarques@hotmail.com
Status Recruiting
Phase N/A
Start date February 1, 2023
Completion date July 2024

See also
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Completed NCT03783845 - The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients Phase 4