Clinical Trials Logo

Clinical Trial Summary

Modified radical mastectomy may be associated with severe post-operative pain, leading to chronic pain syndrome which usually requires optimal perioperative pain management.


Clinical Trial Description

Patients will be randomly into two equal groups (40 patients each) according to the adjuvant added to the local anesthetic (bupivacaine) in the serratus anterior plane block using a computer-generated random numbers concealed in sealed opaque envelopes. Group B: The patients will receive 20 ml of 0.5% bupivacaine plus 5 ml 0.9% normal saline with total volume 25 ml. Group BM: The patients will receive 20 ml of 0.5% bupivacaine plus 150 mg magnesium sulphate in 0.9% normal saline with a total volume of 25 ml. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04429893
Study type Interventional
Source Alexandria University
Contact Rehab A. Abd Elaziz, Ass. Prof.
Phone 01001073703
Email trcium2002@yahoo.com
Status Recruiting
Phase Phase 2/Phase 3
Start date January 1, 2022
Completion date September 2022

See also
  Status Clinical Trial Phase
Recruiting NCT01417923 - The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain Phase 4
Completed NCT03472521 - Prevention of Persistent Opioid Use in Mothers Phase 4
Not yet recruiting NCT03249025 - Lidocaine-Ketamine for Management of Chronic Pain N/A
Enrolling by invitation NCT06359561 - Assessment of Effectiveness and Stimulation Coverage of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Patients With Cervical Lead Placement
Recruiting NCT05877274 - Sodium Channel Mutations in Patient With the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
Completed NCT03317782 - NoL Index Variations Before and After a Stellate Ganglion Block
Completed NCT04199858 - Electrophysiological Correlates of Nocebo Effects on Pain N/A
Recruiting NCT05491499 - Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
Active, not recruiting NCT05090683 - Evaluation of a Mind-body Based Application for the Treatment of Chronic/Persistent Pain. N/A
Completed NCT04197154 - Pain-related Fear as a Facilitator of Nocebo Hyperalgesia N/A
Completed NCT04209764 - Prevalence of Pain in the Departments of Surgery and Oncoematology of a Children's Hospital
Recruiting NCT06071988 - Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy Phase 3
Recruiting NCT06071936 - Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy Phase 3
Recruiting NCT06072560 - Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain Phase 3
Recruiting NCT06072573 - Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy Phase 3
Recruiting NCT06072001 - Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Phase 3
Recruiting NCT06071949 - Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Phase 3
Recruiting NCT06071975 - Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy Phase 3
Recruiting NCT06071962 - Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain Phase 3
Completed NCT03460717 - Thermal Micro-cautery for Painful Knee Osteoarthritis N/A